Western Blot (WB)
(Western blot analysis of UROP11 in mouse spleen tissue lysate with UROP11 antibody at (A) 1 and (B) 2 μg/mL.)
Rabbit UROP11 Polyclonal Antibody | anti-Apba1 antibody
UROP11 Antibody
Gene Names
Apba1; X11; Mint; Mint1; Lin-10; Urop11; X11alpha; 6430513E09Rik
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
UROP11 Antibody is affinity chromatography purified via peptide column.
Synonyms
UROP11; Polyclonal Antibody; UROP11 Antibody; X11; Mint; Mint1; Lin-10; Urop11; X11alpha; 6430513E09Rik; Amyloid beta A4 precursor protein-binding family A member 1; Adapter protein X11alpha; Mint-1; amyloid beta (A4) precursor protein binding; family A; member 1; anti-Apba1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
UROP11 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
110
Applicable Applications for anti-Apba1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
UROP11 antibody can be used for detection of UROP11 by Western blot at 1 - 2 mug/mL. Despite its predicted molecular weight, UROP11 often migrates at a much higher apparent size in SDS-PAGE.
Conjugate
Unconjugated
Immunogen
UROP11 antibody was raised against a 12 amino acid synthetic peptide near the center of the mouse UROP11.
Buffer
UROP11 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
UROP11 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of UROP11 in mouse spleen tissue lysate with UROP11 antibody at (A) 1 and (B) 2 μg/mL.)
Western Blot (WB)
(Western blot analysis of UROP11 in mouse spleen tissue lysate with UROP11 antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-Apba1 antibody
UROP11 Antibody: Upregulated obese product 11 (UROP11) was isolated from subtractive library for mouse hypothalamus. It is detected in numerous tissues and is upregulated in the hypothalamus and adipocytes in obese mice. UROP11 is also observed in human neural and lymphoid tissues; its expression appears to be regulated by the level of lymphoid activation. Urop11 expression is strongly upregulated both in vivo in mouse hypothalamus and in vitro in mouse neural cell lines after treatment with leptin, indicating Urop11 is a target of leptin activity and thus may play a role in obesity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
91,669 Da
NCBI Official Full Name
UROP11-110
NCBI Official Synonym Full Names
amyloid beta (A4) precursor protein binding, family A, member 1
NCBI Official Symbol
Apba1
NCBI Official Synonym Symbols
X11; Mint; Mint1; Lin-10; Urop11; X11alpha; 6430513E09Rik
NCBI Protein Information
amyloid beta A4 precursor protein-binding family A member 1; mint-1; UROP11-110; adapter protein X11alpha; neuron-specific X11 protein; neuronal Munc18-1-interacting protein 1
UniProt Protein Name
Amyloid beta A4 precursor protein-binding family A member 1
Protein Family
UniProt Gene Name
Apba1
UniProt Synonym Gene Names
Mint1; X11; Mint-1
UniProt Entry Name
APBA1_MOUSE
Uniprot Description
APBA1: Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta- amyloid precursor protein (APP) and hence formation of beta-APP.
Protein type: Adaptor/scaffold
Cellular Component: Golgi apparatus; protein complex; membrane; cell; cytoplasm; plasma membrane; intracellular; nucleus
Molecular Function: protein binding; phosphatidylinositol-4,5-bisphosphate binding; beta-amyloid binding; protein complex binding; PDZ domain binding
Biological Process: intracellular protein transport; synaptic transmission; protein transport; glutamate secretion; in utero embryonic development; transport; regulation of gene expression; multicellular organism growth; gamma-aminobutyric acid secretion; locomotory behavior
Research Articles on Apba1
Similar Products
Product Notes
The Apba1 apba1 (Catalog #AAA150387) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UROP11 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's UROP11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). UROP11 antibody can be used for detection of UROP11 by Western blot at 1 - 2 mug/mL. Despite its predicted molecular weight, UROP11 often migrates at a much higher apparent size in SDS-PAGE. Researchers should empirically determine the suitability of the Apba1 apba1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UROP11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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