Western Blot (WB)
(WB Suggested Anti-UHRF1 AntibodyPositive Control: Lane 1: 60ug HCT116 lysate Lane 2: 60ug HCT116 lysate + siRNAPrimary Antibody Dilution : 1:1000Secondary Antibody : Anti rabbit-HRPSecondry Antibody Dilution : 1:5,000Submitted by: Chinweike Ukomadu, Brigham and Women's Hospital, Boston)
Rabbit UHRF1 Polyclonal Antibody | anti-UHRF1 antibody
UHRF1 antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-UHRF1 AntibodyPositive Control: Lane 1: 60ug HCT116 lysate Lane 2: 60ug HCT116 lysate + siRNAPrimary Antibody Dilution : 1:1000Secondary Antibody : Anti rabbit-HRPSecondry Antibody Dilution : 1:5,000Submitted by: Chinweike Ukomadu, Brigham and Women's Hospital, Boston)
Western Blot (WB)
(WB Suggested Anti-UHRF1 AntibodyPositive Control: Lane 1: 60ug HCT116 lysate Lane 2: 60ug HCT116 lysate + siRNAPrimary Antibody Dilution : 1:1000Secondary Antibody : Anti rabbit-HRPSecondry Antibody Dilution : 1:5,000Submitted by: Chinweike Ukomadu, Brigham and Women's Hospital, Boston)
Western Blot (WB)
(WB Suggested Anti-UHRF1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Stomach)
Western Blot (WB)
(WB Suggested Anti-UHRF1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Stomach)
Target Description: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014]
Research Articles on UHRF1
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Product Notes
The UHRF1 (Catalog #AAA3204403) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UHRF1 antibody - N-terminal region reacts with Guinea Pig, Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's UHRF1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the UHRF1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: MGVFAVPPLS ADTMWIQVRT MDGRQTHTVD SLSRLTKVEE LRRKIQELFH. It is sometimes possible for the material contained within the vial of "UHRF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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