Rabbit anti-Human TRAIP Polyclonal Antibody | anti-TRAIP antibody
Polyclonal Antibody to TRAIP (TRIP)
Gene Names
TRAIP; TRIP; SCKL9; RNF206
Reactivity
Human
Applications
Immunoprecipitation, Immunohistochemistry, Western Blot
Purity
Serum
Synonyms
TRAIP; Polyclonal Antibody; Polyclonal Antibody to TRAIP (TRIP); RNF206; TRIP; RING finger protein 206; TRAF-interacting protein; Antibody to TRAIP (TRIP); Anti-TRAIP (TRIP) Antibody; TRAIP (TRIP) Antibody; anti-TRAIP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Serum
Form/Format
50 ul sera
Sequence Length
469
Applicable Applications for anti-TRAIP antibody
Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB)
Application Notes
WB: 1: 1000-1: 2000
IHC (paraffin): 1: 1000-1: 5000
IP: 1: 50-1: 200
IHC (paraffin): 1: 1000-1: 5000
IP: 1: 50-1: 200
Immunogen Information
A synthetic peptide of human TRIP (amino acids 294-313 ESPAPVEVNLKLRRPSFRDD) was used as immunogen for this antibody
Antigen
TRAIP (TRIP)
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
Related Product Information for anti-TRAIP antibody
TRIP (TRAF-interacting protein), also known as TRAIP is a component of receptor-TRAF signaling complexes. Structurally it contains an N-terminal RING finger motif and a putative coiled-coil domain and composed of 469amino acid approximately. TRIP has been shown to associate with TRNFR2 or CD30 signaling complexes through its interaction with TRAF proteins and inhibit TRAF2-mediated NF-kB activation. The recruitment of different TRAFs and TRAF associated proteins like TRIP to receptor complexes can help regulate and provide specificity to the intracellular signals triggered by the cell surface receptors.
Product Categories/Family for anti-TRAIP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
53,294 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase TRAIP
NCBI Official Synonym Full Names
TRAF interacting protein
NCBI Official Symbol
TRAIP
NCBI Official Synonym Symbols
TRIP; SCKL9; RNF206
NCBI Protein Information
E3 ubiquitin-protein ligase TRAIP
UniProt Protein Name
E3 ubiquitin-protein ligase TRAIP
Protein Family
UniProt Gene Name
TRAIP
UniProt Synonym Gene Names
RNF206; TRIP
NCBI Description
This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008]
Uniprot Description
TRAIP: Inhibits activation of NF-kappa-B mediated by TNF.
Protein type: EC 6.3.2.-; Ligase; Nucleolus; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 3p21.31
Molecular Function: protein binding
Biological Process: apoptosis; cell proliferation
Disease: Seckel Syndrome 9
Research Articles on TRAIP
Similar Products
Product Notes
The TRAIP traip (Catalog #AAA668821) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to TRAIP (TRIP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRAIP can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB). WB: 1: 1000-1: 2000 IHC (paraffin): 1: 1000-1: 5000 IP: 1: 50-1: 200. Researchers should empirically determine the suitability of the TRAIP traip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRAIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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