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Western Blot (WB) (Western blot analysis of anti-TRAIP Antibody (C-term) in HepG2 cell line lysates (35ug/lane). TRAIP(arrow) was detected using the purified Pab.)

Rabbit anti-Human TRAIP Polyclonal Antibody | anti-TRAIP antibody

TRAIP Antibody (C-term)

Gene Names
TRAIP; TRIP; RNF206
Reactivity
Human
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TRAIP; Polyclonal Antibody; TRAIP Antibody (C-term); E3 ubiquitin-protein ligase TRAIP; 632-; RING finger protein 206; TRAF-interacting protein; RNF206; TRIP; anti-TRAIP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TRAIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-356 amino acids from the C-terminal region of human TRAIP.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
328-356
Sequence Length
469
Applicable Applications for anti-TRAIP antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of anti-TRAIP Antibody (C-term) in HepG2 cell line lysates (35ug/lane). TRAIP(arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of anti-TRAIP Antibody (C-term) in HepG2 cell line lysates (35ug/lane). TRAIP(arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with TRAIP antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with TRAIP antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Related Product Information for anti-TRAIP antibody
TRAIP is a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
Product Categories/Family for anti-TRAIP antibody
References
Wu,C., Proteomics 7 (11), 1775-1785 (2007) Regamey,A., J. Exp. Med. 198 (12), 1959-1964 (2003)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53294
NCBI Official Full Name
E3 ubiquitin-protein ligase TRAIP
NCBI Official Synonym Full Names
TRAF interacting protein
NCBI Official Symbol
TRAIP
NCBI Official Synonym Symbols
TRIP; RNF206
NCBI Protein Information
E3 ubiquitin-protein ligase TRAIP
UniProt Protein Name
E3 ubiquitin-protein ligase TRAIP
UniProt Gene Name
TRAIP
UniProt Synonym Gene Names
RNF206; TRIP
UniProt Entry Name
TRAIP_HUMAN

NCBI Description

This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008]

Uniprot Description

TRAIP: Inhibits activation of NF-kappa-B mediated by TNF.

Protein type: Nucleolus; Ubiquitin ligase; Ubiquitin conjugating system; Ligase; EC 6.3.2.-

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: perinuclear region of cytoplasm; nucleolus

Molecular Function: protein binding; zinc ion binding; receptor signaling protein activity; ubiquitin-protein ligase activity; ligase activity

Biological Process: cell proliferation; apoptosis; protein ubiquitination; signal transduction

Research Articles on TRAIP

Similar Products

Product Notes

The TRAIP traip (Catalog #AAA9206483) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 328-356. The TRAIP Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRAIP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the TRAIP traip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRAIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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