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Western Blot (WB) (Western blot analysis of extracts from HepG2 cells using TESK2 antibody.)

Rabbit TESK2 Polyclonal Antibody | anti-TESK2 antibody

TESK2 Antibody

Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
TESK2; Polyclonal Antibody; TESK2 Antibody; Dual specificity testis specific protein kinase 2; Dual specificity testis-specific protein kinase 2; MGC29168; OTTHUMP00000009093; RP23-109A3.2; Tesk2; TESK2_HUMAN; Testicular protein kinase 2; Testis specific kinase 2; anti-TESK2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
TESK2 antibody detects endogenous levels of total TESK2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
488
Applicable Applications for anti-TESK2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthesized peptide
Subcellular Location
Nucleus.
Tissue Specificity
Predominantly expressed in testis and prostate. Found predominantly in non-germinal Sertoli cells.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit
Similarity
Pig (82%), Bovine (91%), Horse (100%), Sheep (91%), Rabbit (89%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of extracts from HepG2 cells using TESK2 antibody.)

Western Blot (WB) (Western blot analysis of extracts from HepG2 cells using TESK2 antibody.)

Western Blot (WB)

(Western blot analysis of extracts from rat brain, using TESK2 Antibody.)

Western Blot (WB) (Western blot analysis of extracts from rat brain, using TESK2 Antibody.)
Related Product Information for anti-TESK2 antibody
Function: Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis.
Similarity: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 65 kD
Predicted: 64 kDa
NCBI Official Full Name
dual specificity testis-specific protein kinase 2 isoform 2
NCBI Official Synonym Full Names
testis associated actin remodelling kinase 2
NCBI Official Symbol
TESK2
NCBI Protein Information
dual specificity testis-specific protein kinase 2
UniProt Protein Name
Dual specificity testis-specific protein kinase 2
UniProt Gene Name
TESK2

NCBI Description

This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Uniprot Description

Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis.

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Product Notes

The TESK2 tesk2 (Catalog #AAA9606249) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TESK2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TESK2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the TESK2 tesk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TESK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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