Rabbit TESK1 Polyclonal Antibody | anti-TESK1 antibody

TESK1 Antibody

Cat. Num. AAA9605468

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, ELISA
• Purity: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Synonyms: TESK1; Polyclonal Antibody; TESK1 Antibody; Dual specificity testis specific protein kinase 1; Dual specificity testis-specific protein kinase 1; TESK 1; TESK1_HUMAN; Testicular protein kinase 1; Testis specific kinase 1; Testis specific protein kinase 1; anti-TESK1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: TESK1 antibody detects endogenous levels of total TESK1
• Purity/Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Form/Format: Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)
• Sequence Length: 466

• Applicable Applications for anti-TESK1 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthesized peptide
• Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog
• Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%)
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of extracts from rat heart cells using TESK1 antibody.)

Related Product Information for anti-TESK1 antibody

Function: Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Probably plays a central role at and after the meiotic phase of spermatogenesis (By similarity).
Subunit Structure: Interacts with TAOK2; leading to inhibit TAOK2 activity. Interacts with SPRED1; leading to inhibit activity (By similarity). Interacts with SPRY4.
Post-translational Modifications: Autophosphorylated on serine and tyrosine residues.
Similarity: The extracatalytic C-terminal part is highly rich in proline residues. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

NCBI and Uniprot Product Information

• NCBI GI #: 970841896
• NCBI GeneID: 7016
• NCBI Accession #: NP_001305159.1
• NCBI GenBank Nucleotide #: NM_001318230.1
• UniProt Accession #: Q15569; Q8IXZ8
• Molecular Weight: Observed: 68 kD; Predicted: 68 kDa
• NCBI Official Full Name: dual specificity testis-specific protein kinase 1 isoform 2
• NCBI Official Synonym Full Names: testis associated actin remodelling kinase 1
• NCBI Official Symbol: TESK1
• NCBI Protein Information: dual specificity testis-specific protein kinase 1
• UniProt Protein Name: Dual specificity testis-specific protein kinase 1
• Protein Family: Dual specificity testis-specific protein kinase
• UniProt Gene Name: TESK1

NCBI Description

This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Uniprot Description

Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Probably plays a central role at and after the meiotic phase of spermatogenesis ().