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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/35.)

Rabbit anti-Human SLIT1 Polyclonal Antibody | anti-SLIT1 antibody

SLIT1 Antibody

Gene Names
SLIT1; MEGF4; SLIL1; SLIT3; SLIT-1
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
SLIT1; Polyclonal Antibody; SLIT1 Antibody; MEGF4; SLIL1; SLIT3; SLIT-1; anti-SLIT1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total SLIT1 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
2.3 mg/ml (varies by lot)
Sequence Length
1534
Applicable Applications for anti-SLIT1 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:25-1:100
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to a region derived from internal residues of human slit homolog 1 (Drosophila)
Target Name
SLIT1
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/35.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/35.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using at dilution 1/35.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using at dilution 1/35.)
Related Product Information for anti-SLIT1 antibody
Slit homolog 1 protein is a protein that in humans is encoded by the SLIT1 gene. Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions By similarity. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
Product Categories/Family for anti-SLIT1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
90,633 Da
NCBI Official Full Name
slit homolog 1 protein
NCBI Official Synonym Full Names
slit guidance ligand 1
NCBI Official Symbol
SLIT1
NCBI Official Synonym Symbols
MEGF4; SLIL1; SLIT3; SLIT-1
NCBI Protein Information
slit homolog 1 protein
UniProt Protein Name
Slit homolog 1 protein
Protein Family
UniProt Gene Name
SLIT1
UniProt Synonym Gene Names
KIAA0813; MEGF4; SLIL1; Slit-1; Multiple EGF-like domains protein 4
UniProt Entry Name
SLIT1_HUMAN

Uniprot Description

SLIT1: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 10q23.3-q24

Cellular Component: extracellular space

Molecular Function: heparan sulfate proteoglycan binding; Roundabout binding; calcium ion binding

Biological Process: axon extension involved in axon guidance; chemorepulsion involved in embryonic olfactory bulb interneuron migration; axon guidance; establishment of nucleus localization; spinal cord development; negative chemotaxis; motor axon guidance; negative regulation of synaptogenesis; negative regulation of axon extension involved in axon guidance; forebrain morphogenesis; dorsal/ventral axon guidance; retinal ganglion cell axon guidance

Research Articles on SLIT1

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Product Notes

The SLIT1 slit1 (Catalog #AAA9412267) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLIT1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLIT1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the SLIT1 slit1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLIT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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