Immunohistochemistry (IHC)
(Anti-SLIT1 / SLIT-1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit anti-Mouse, Human SLIT1 Polyclonal Antibody | anti-SLIT1 antibody
Anti-SLIT1 Antibody (aa83-113) IHC-plus
WB (1:1000)
For long term storage store at -20 degree C.
Immunohistochemistry (IHC)
(Anti-SLIT1 / SLIT-1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-SLIT1 / SLIT-1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Western Blot (WB)
(SLIT1 Antibody western blot of mouse heart tissue lysates (35 ug/lane). The SLIT1 antibody detected the SLIT1 protein (arrow).)
Western Blot (WB)
(SLIT1 Antibody western blot of mouse heart tissue lysates (35 ug/lane). The SLIT1 antibody detected the SLIT1 protein (arrow).)
NCBI and Uniprot Product Information
Uniprot Description
SLIT1: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 10q23.3-q24
Cellular Component: cell; extracellular space; proteinaceous extracellular matrix
Molecular Function: calcium ion binding; heparin binding; Roundabout binding
Biological Process: axon extension involved in axon guidance; axon guidance; chemorepulsion involved in embryonic olfactory bulb interneuron migration; dorsal/ventral axon guidance; establishment of nucleus localization; forebrain morphogenesis; motor axon guidance; negative chemotaxis; negative regulation of synaptogenesis; regulation of axonogenesis; retinal ganglion cell axon guidance
Research Articles on SLIT1
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Product Notes
The SLIT1 slit1 (Catalog #AAA2400350) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SLIT1 Antibody (aa83-113) IHC-plus reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLIT1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P (1:10 - 1:100) WB (1:1000). Researchers should empirically determine the suitability of the SLIT1 slit1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLIT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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