Human fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) ELISA Kit | FABP3 elisa kit

Human heart fatty acid binding protein, h-FABP ELISA Kit

Cat. Num. AAA701517

• Gene Names: FABP3; MDGI; FABP11; H-FABP; M-FABP; O-FABP
• Reactivity: Human
• Synonyms: fatty acid binding protein 3; muscle and heart (mammary-derived growth inhibitor); Human heart fatty acid binding protein; h-FABP ELISA Kit; FABP11; H-FABP; MDGI; O-FABP; Fatty acid-binding protein 3; muscle; fatty acid binding protein 11; mammary-derived growth inhibitor; FABP3 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of Human FABP3. No significant cross-reactivity or interference between Human FABP3 and analogues was observed.
• Sequence Length: 133

• Samples: Serum, urine, tissue homogenates
• Assay Type: Sandwich
• Detection Range: 0.312 ng/ml-20 ng/ml
• Sensitivity: 0.078 ng/ml
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%; Three samples of known concentration were tested twenty times on one plate to assess.; Inter-assay Precision (Precision between assays): CV% is less than 10%; Three samples of known concentration were tested in twenty assays to assess.
• Detection Wavelength: 450 nm
• Sample Volume: 50-100ul
• Protein Biological Process 1: Transport
• Protein Biological Process 3: Transport
• Preparation and Storage: Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for FABP3 elisa kit

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for h-FABP has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any h-FABP present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for h-FABP is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of h-FABP bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 4758328
• NCBI GeneID: 2170
• NCBI Accession #: NP_004093.1
• NCBI GenBank Nucleotide #: NM_004102.3
• UniProt Accession #: P05413; Q5VV93; Q99957; B2RAB6
• Molecular Weight: 14,858 Da
• NCBI Official Full Name: fatty acid-binding protein, heart
• NCBI Official Synonym Full Names: fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
• NCBI Official Symbol: FABP3
• NCBI Official Synonym Symbols: MDGI; FABP11; H-FABP; M-FABP; O-FABP
• NCBI Protein Information: fatty acid-binding protein, heart; fatty acid binding protein 11; mammary-derived growth inhibitor; muscle fatty acid-binding protein; Fatty acid-binding protein 3, muscle; heart-type fatty acid-binding protein
• UniProt Protein Name: Fatty acid-binding protein, heart
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP3
• UniProt Synonym Gene Names: FABP11; MDGI; H-FABP; MDGI; M-FABP
• UniProt Entry Name: FABPH_HUMAN

NCBI Description

The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.