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Testing Data (Primary: Anti-C14orf156 at 1/1000 dilution)

Rabbit SLIRP/C14orf156 Polyclonal Antibody | anti-SLIRP/C14orf156 antibody

SLIRP/C14orf156 Polyclonal Antibody

Gene Names
SLIRP; DC50; PD04872; C14orf156
Reactivity
Human, Mouse, Rat, Pig, Rabbit
Applications
Western Blot, Immunohistochemistry
Purity
affinity purified by Protein A
Synonyms
SLIRP/C14orf156; Polyclonal Antibody; SLIRP/C14orf156 Polyclonal Antibody; C14orf156; Chromosome 14 open reading frame 156; DC50; DC23; PD04872; SLIRP; SRA stem loop interacting RNA binding protein; mitochondrial; anti-SLIRP/C14orf156 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Pig, Rabbit
Clonality
Polyclonal
Specificity
SLIRP/C14orf156 Polyclonal Antibody detects endogenous levels of SLIRP/C14orf156 protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 120% Glycerol.
Applicable Applications for anti-SLIRP/C14orf156 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-2000
IHC-P: 1:100-500
Immunogen
KLH conjugated synthetic peptide derived from human SLIRP/C14orf156:31-100/109
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -39 degree C long term. Avoid freeze-thaw cycles.

Testing Data

(Primary: Anti-C14orf156 at 1/1000 dilution)

Testing Data (Primary: Anti-C14orf156 at 1/1000 dilution)

Immunohistochemistry (IHC)

(Paraformaldehyde-fixed, paraffin embedded (Mouse liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLIRP/C14orf156) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C)

Immunohistochemistry (IHC) (Paraformaldehyde-fixed, paraffin embedded (Mouse liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLIRP/C14orf156) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C)
Related Product Information for anti-SLIRP/C14orf156 antibody
Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]).[supplied by OMIM, Mar 2008]

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12,349 Da
NCBI Official Full Name
SRA stem-loop-interacting RNA-binding protein, mitochondrial
NCBI Official Synonym Full Names
SRA stem-loop interacting RNA binding protein
NCBI Official Symbol
SLIRP
NCBI Official Synonym Symbols
DC50; PD04872; C14orf156
NCBI Protein Information
SRA stem-loop-interacting RNA-binding protein, mitochondrial
UniProt Protein Name
SRA stem-loop-interacting RNA-binding protein, mitochondrial
UniProt Gene Name
SLIRP
UniProt Synonym Gene Names
C14orf156
UniProt Entry Name
SLIRP_HUMAN

NCBI Description

Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]).[supplied by OMIM]

Uniprot Description

SLIRP: RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.

Protein type: RNA-binding; Nuclear receptor co-regulator; Mitochondrial; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: mitochondrion; perinuclear region of cytoplasm; acrosome; nucleus; ribonucleoprotein complex

Molecular Function: nucleotide binding

Biological Process: sperm motility; transcription, DNA-dependent; regulation of transcription, DNA-dependent; single fertilization; spermatid development

Research Articles on SLIRP/C14orf156

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Product Notes

The SLIRP/C14orf156 slirp (Catalog #AAA3015401) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLIRP/C14orf156 Polyclonal Antibody reacts with Human, Mouse, Rat, Pig, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's SLIRP/C14orf156 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-2000 IHC-P: 1:100-500. Researchers should empirically determine the suitability of the SLIRP/C14orf156 slirp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLIRP/C14orf156, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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