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Immunohistochemistry (IHC) (Immunohistochemical staining of paraffin-embedded DLD-1 xenograft using SLC26A8 antibody at a dilution of 1:500)

Rabbit SLC26A8 Polyclonal Antibody | anti-SLC26A8 antibody

SLC26A8 antibody

Applications
Immunohistochemistry, Western Blot
Purity
SLC26A8 antibody was purified by antigen-affinity chromatography
Synonyms
SLC26A8; Polyclonal Antibody; SLC26A8 antibody; Polyclonal SLC26A8; Anti-SLC26A8; FLJ32714; TAT1; testis anion transporter 1; SLCA8 26; anion exchange transporter; SLCA8-26; anion transporter/exchanger-8; anti-SLC26A8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
SLC26A8 antibody was purified by antigen-affinity chromatography
Form/Format
Supplied as a concentrated soloution containing 1X PBS, 1% BSA, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
0.83 mg/ml (varies by lot)
Sequence Length
768
Applicable Applications for anti-SLC26A8 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:100-1:500
WB: 1:500-1:3000
Biological Significance
This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. This gene is expressed primarily in spermatocytes.
Cross-Reactivity
Human
Immunogen
SLC26A8 antibody was raised in rabbit using a recombinant protein fragment contain a sequence corresponding to a region within amino acids 613 and 850  of SLC26A8
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemical staining of paraffin-embedded DLD-1 xenograft using SLC26A8 antibody at a dilution of 1:500)

Immunohistochemistry (IHC) (Immunohistochemical staining of paraffin-embedded DLD-1 xenograft using SLC26A8 antibody at a dilution of 1:500)

Western Blot (WB)

(Western blot analysis of 30 ug of whole cell lysate (A: Molt-4) using a 7.5 % SDS PAGE gel and SLC26A8 antibody at a dilution of 1:1000)

Western Blot (WB) (Western blot analysis of 30 ug of whole cell lysate (A: Molt-4) using a 7.5 % SDS PAGE gel and SLC26A8 antibody at a dilution of 1:1000)
Related Product Information for anti-SLC26A8 antibody
Affinity purified Rabbit polyclonal SLC26A8 antibody
Product Categories/Family for anti-SLC26A8 antibody

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
109 kDa
UniProt Protein Name
Testis anion transporter 1
Protein Family
UniProt Gene Name
SLC26A8
UniProt Entry Name
S26A8_HUMAN

Uniprot Description

SLC26A8: Acts as a DIDS-sensitive anion exchanger mediating chloride, sulfate and oxalate transport. May fulfill critical anion exchange functions in male germ line during meiosis and hence may play a role in spermatogenesis. May be involved in a new regulatory pathway linking sulfate transport to RhoGTPase signaling in male germ cells. A critical component of the sperm annulus that is essential for correct sperm tail differentiation and motility and hence male fertility. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Transporter, SLC family; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p21

Cellular Component: integral to membrane; plasma membrane

Molecular Function: protein binding; chloride channel activity; anion:anion antiporter activity; sulfate transmembrane transporter activity; oxalate transmembrane transporter activity; secondary active sulfate transmembrane transporter activity

Biological Process: sperm motility; meiotic cell cycle; multicellular organismal development; sulfate transport; chloride transport; oxalate transport; anion transport; sperm capacitation

Disease: Spermatogenic Failure 3

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Product Notes

The SLC26A8 slc26a8 (Catalog #AAA835684) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's SLC26A8 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:100-1:500 WB: 1:500-1:3000. Researchers should empirically determine the suitability of the SLC26A8 slc26a8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC26A8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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