SDS-Page
Glypican 2/GPC2 Active Protein | CD70 active protein
Human CellExp Glypican 2/GPC2, Mouse Recombinant
Gene Names
Gpc2; 2410016G05Rik
Purity
>95%
Synonyms
Glypican 2/GPC2; Human CellExp Glypican 2/GPC2; Mouse Recombinant; CD70; CD27LG; TNFSF7; TNFSF7G; CD27L; CD70 active protein
Host
HEK293 cells
Purity/Purification
>95%
Form/Format
Lyophilized powder. Lyophilized from 0.22um filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Sequence
aaHis22-Ser556
Gene Source
Mouse
Endotoxin
<1 EU/ug by LAL method
Biological Activity
Immobilized Mouse CD27, Mouse IgG2a Fc Tag, at 2 ug/mL (100 uL/well) can bind Mouse CD27 Ligand (active trimer)with a linear range of 0.1-4 ng/mL
Measured by its binding ability in a functional ELISA
Measured by its binding ability in a functional ELISA
Reconstitution Instruction
Reconstitute in sterile deionized water to a concentration of 100 ug/ml.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Centrifuge the vial prior to opening.
Shelf life: ~12 months
SDS-Page
SDS-Page
Testing Data
Testing Data
Related Product Information for CD70 active protein
Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L/CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation.
Product Categories/Family for CD70 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
63,344 Da
NCBI Official Full Name
glypican-2
NCBI Official Synonym Full Names
glypican 2 (cerebroglycan)
NCBI Official Symbol
Gpc2
NCBI Official Synonym Symbols
2410016G05Rik
NCBI Protein Information
glypican-2
UniProt Protein Name
Glypican-2
Protein Family
UniProt Gene Name
Gpc2
UniProt Entry Name
GPC2_MOUSE
Uniprot Description
GPC2: Cell surface proteoglycan that bears heparan sulfate. May fulfill a function related to the motile behaviors of developing neurons. Belongs to the glypican family.
Protein type: Membrane protein, GPI anchor
Cellular Component: proteinaceous extracellular matrix; membrane; endoplasmic reticulum; extracellular region; plasma membrane
Molecular Function: heparan sulfate proteoglycan binding
Biological Process: neuron differentiation; smoothened signaling pathway
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Product Notes
The CD70 gpc2 (Catalog #AAA8400111) is an Active Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: aaHis22-Se r556. It is sometimes possible for the material contained within the vial of "Glypican 2/GPC2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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