Western Blot (WB)
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Human testis tissue, A375 cells, Primary antibody: 160282(SLC1A6 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)
Rabbit SLC1A6 Polyclonal Antibody | anti-SLC1A6 antibody
SLC1A6 Rabbit pAb
Gene Names
SLC1A6; EAAT4
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
SLC1A6; Polyclonal Antibody; SLC1A6 Rabbit pAb; solute carrier family 1 (high affinity aspartate/glutamate transporter); member 6; anti-SLC1A6 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-SLC1A6 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
ELISA: 1:2000-1:5000
IHC: 1:50-1:200
ELISA: 1:2000-1:5000
IHC: 1:50-1:200
Immunogen
Synthetic peptide of human SLC1A6
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Human testis tissue, A375 cells, Primary antibody: 160282(SLC1A6 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)
Western Blot (WB)
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Human testis tissue, A375 cells, Primary antibody: 160282(SLC1A6 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 160282(SLC1A6 Antibody) at dilution 1/40.(Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 160282(SLC1A6 Antibody) at dilution 1/40.(Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 160282(SLC1A6 Antibody) at dilution 1/40. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 160282(SLC1A6 Antibody) at dilution 1/40. (Original magnification: ×200))
Related Product Information for anti-SLC1A6 antibody
Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
Product Categories/Family for anti-SLC1A6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
61,565 Da
NCBI Official Full Name
excitatory amino acid transporter 4 isoform 1
NCBI Official Synonym Full Names
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
NCBI Official Symbol
SLC1A6
NCBI Official Synonym Symbols
EAAT4
NCBI Protein Information
excitatory amino acid transporter 4; solute carrier family 1 member 6; sodium-dependent glutamate/aspartate transporter
UniProt Protein Name
Excitatory amino acid transporter 4
Protein Family
UniProt Gene Name
SLC1A6
UniProt Synonym Gene Names
EAAT4
UniProt Entry Name
EAA4_HUMAN
Uniprot Description
SLC1A6: Transports L-glutamate and also L- and D-aspartate. Seems to act as a symport by cotransporting sodium. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A6 subfamily.
Protein type: Transporter; Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 19p13.12
Cellular Component: Golgi apparatus; membrane; integral to plasma membrane; plasma membrane
Molecular Function: L-aspartate transmembrane transporter activity; sodium:dicarboxylate symporter activity; L-glutamate transmembrane transporter activity
Biological Process: synaptic transmission; regulation of membrane potential; L-glutamate transport; ion transport; aspartate transport; transmembrane transport
Research Articles on SLC1A6
Similar Products
Product Notes
The SLC1A6 slc1a6 (Catalog #AAA4754668) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC1A6 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SLC1A6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 ELISA: 1:2000-1:5000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the SLC1A6 slc1a6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC1A6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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