Rabbit anti-Mouse Signaling Lymphocytic Activation Molecule Family Polyclonal Antibody | anti-SLAMF5 antibody
Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 5 (SLAMF5)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Sample: Mouse Liver lysate;Primary Ab: 1ug/ml Rabbit Anti-Mouse SLAMF5 AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047) )
NCBI and Uniprot Product Information
Uniprot Description
CD84: Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain- containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell surface; Immunoglobulin superfamily; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1 H3|1 79.54 cM
Cellular Component: extracellular exosome; integral component of membrane; membrane; plasma membrane
Molecular Function: identical protein binding
Biological Process: adaptive immune response; cell adhesion; immune system process; innate immune response; negative regulation of granulocyte macrophage colony-stimulating factor production; negative regulation of interleukin-10 secretion; negative regulation of interleukin-18 production; negative regulation of interleukin-6 secretion; negative regulation of mast cell activation; negative regulation of mast cell degranulation; positive regulation of MAPK cascade; positive regulation of monocyte chemotactic protein-1 production; positive regulation of NF-kappaB transcription factor activity; positive regulation of tumor necrosis factor secretion; regulation of lipopolysaccharide-mediated signaling pathway; regulation of macrophage activation; regulation of store-operated calcium entry
Research Articles on SLAMF5
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Product Notes
The SLAMF5 cd84 (Catalog #AAA2026060) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 5 (SLAMF5) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Signaling Lymphocytic Activation Molecule Family can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). . Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the SLAMF5 cd84 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Signaling Lymphocytic Activation Molecule Family, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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