Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Mouse Signal Transducer And Activator Of Transcription 6 (STAT6) Polyclonal Antibody | anti-STAT6 antibody
Polyclonal Antibody to Signal Transducer And Activator Of Transcription 6 (STAT6)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-L VVIVHGNQDN NAKATILWDN AFSEMDRVPF VVAERVPWEK MCETLNLKFM AEVGTSRGLL PEHFLFLAQK IFNDNSLSVE AFQHRCVSWS QFNKEILLGR GFTFWQWFDG VLDLTKRCLR SYWSDRLIIG FISKQYVTSL LLNEPDGTFL LRFSDSEIGG ITIAHVIRGQ DGSSQIENIQ PFSAKDLSIR SLGDRIRDLA QLKNLYPKKP KDE
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
NCBI and Uniprot Product Information
Uniprot Description
STAT6: transcription factor of the STAT family. Plays a central role in IL4-mediated biological responses. Induces the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. May function in the differentiation of T helper 2 cells and class switch of immunoglobulins. Forms homo- or heterodimers that translocate into the nucleus where they regulate transcription.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 10 D3|10 74.59 cM
Cellular Component: cytoplasm; cytosol; membrane raft; nuclear chromatin; nuclear membrane; nucleoplasm; nucleus
Molecular Function: DNA binding; DNA binding transcription factor activity; identical protein binding; protein binding; protein phosphatase binding; sequence-specific DNA binding; signal transducer activity
Biological Process: cellular response to hydrogen peroxide; cellular response to reactive nitrogen species; cytokine-mediated signaling pathway; mammary gland epithelial cell proliferation; negative regulation of T-helper 2 type immune response; negative regulation of transcription from RNA polymerase II promoter; positive regulation of isotype switching to IgE isotypes; positive regulation of transcription from RNA polymerase II promoter; regulation of cell proliferation; regulation of transcription, DNA-templated; response to cytokine; signal transduction; T-helper 1 cell lineage commitment; transcription, DNA-dependent
Research Articles on STAT6
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Product Notes
The STAT6 stat6 (Catalog #AAA2003086) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Signal Transducer And Activator Of Transcription 6 (STAT6) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Signal Transducer And Activator Of Transcription 6 (STAT6) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the STAT6 stat6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-L VVIVHGNQDN NAKATILWDN AFSEMDRVPF VVAERVPWEK MCETLNLKFM AEVGTSRGLL PEHFLFLAQK IFNDNSLSVE AFQHRCVSWS QFNKEILLGR GFTFWQWFDG VLDLTKRCLR SYWSDRLIIG FISKQYVTSL LLNEPDGTFL LRFSDSEIGG ITIAHVIRGQ DGSSQIENIQ PFSAKDLSIR SLGDRIRDLA QLKNLYPKKP KDE. It is sometimes possible for the material contained within the vial of "Signal Transducer And Activator Of Transcription 6 (STAT6), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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