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Rabbit anti-Human SI Polyclonal Antibody | anti-SI antibody

SI Antibody

Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
SI; Polyclonal Antibody; SI Antibody; Isomaltase; MGC131621; MGC131622; Oligosaccharide alpha 1; 6 glucosidase; sucrase isomaltase alpha glucosidase; sucrase isomaltase; Sucrase-isomaltase; intestinal; SUIS_HUMAN; anti-SI antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
SI Antibody detects endogenous levels of SI.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-SI antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human SI.
Conjugation
Unconjugated
Similarity
Belongs to the glycosyl hydrolase 31 family.
Post Translational Modifications
The precursor is proteolytically cleaved when exposed to pancreatic proteases in the intestinal lumen.Sulfated.
Subunit Structure
The resulting sucrase and isomaltase subunits stay associated with one another in a complex by non-covalent linkages.
Tissue Specificity
Expressed in the poorly differentiated crypt cells of the small intestine as well as in the mature villous cells. Expressed at very low levels in the colon.
Function
Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1, 4- and alpha-1, 6-oligosaccharides.
Note
Brush border.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-SI antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
209,453 Da
NCBI Official Full Name
sucrase-isomaltase, intestinal
NCBI Official Synonym Full Names
sucrase-isomaltase
NCBI Official Symbol
SI
NCBI Protein Information
sucrase-isomaltase, intestinal
UniProt Protein Name
Sucrase-isomaltase, intestinal
Protein Family
UniProt Gene Name
SI

NCBI Description

This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.[provided by RefSeq, Apr 2010]

Uniprot Description

Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides.

Research Articles on SI

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Product Notes

The SI si (Catalog #AAA9631192) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SI Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SI can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the SI si for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SI, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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