Western Blot (WB)
(Western Blot analysis of SH2D1B expression in A-431 using 133285.)
Rabbit anti-Human SH2D1B Polyclonal Antibody | anti-SH2D1B antibody
SH2D1B (SH2 Domain-containing Protein 1B, EWS/FLI1-activated Transcript 2, EAT-2, EAT2) (AP)
Western Blot (WB)
(Western Blot analysis of SH2D1B expression in A-431 using 133285.)
Western Blot (WB)
(Western Blot analysis of SH2D1B expression in A-431 using 133285.)
Western Blot (WB)
(Western Blot analysis of SH2D1B expression in transfected 293T cell line by 133285. Lane 1: SH2D1B transfected lysate (15.3kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of SH2D1B expression in transfected 293T cell line by 133285. Lane 1: SH2D1B transfected lysate (15.3kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008]
Uniprot Description
SH2D1B: Plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 1q23.3
Cellular Component: intracellular
Molecular Function: protein binding, bridging; protein binding
Biological Process: leukocyte activation during immune response; positive regulation of innate immune response; positive regulation of natural killer cell mediated immunity
Research Articles on SH2D1B
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Product Notes
The SH2D1B sh2d1b (Catalog #AAA6394080) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SH2D1B (SH2 Domain-containing Protein 1B, EWS/FLI1-activated Transcript 2, EAT-2, EAT2) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SH2D1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SH2D1B sh2d1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SH2D1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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