Western Blot (WB)
(Western blot analysis of SERPINB7 Antibody (Center) in HL-60 cell line lysates (35ug/lane). SERPINB7 (arrow) was detected using the purified Pab.)
Rabbit anti-Human SERPINB7 Polyclonal Antibody | anti-SERPINB7 antibody
SERPINB7 Antibody (Center)
Western Blot (WB)
(Western blot analysis of SERPINB7 Antibody (Center) in HL-60 cell line lysates (35ug/lane). SERPINB7 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of SERPINB7 Antibody (Center) in HL-60 cell line lysates (35ug/lane). SERPINB7 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human kidney carcinoma reacted with SERPINB7 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human kidney carcinoma reacted with SERPINB7 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(SERPINB7 Antibody (Center) flow cytometric analysis of HL60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(SERPINB7 Antibody (Center) flow cytometric analysis of HL60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Wang,Z.H., et.al., Zhonghua Yi Xue Za Zhi 86 (19), 1337-1341 (2006)
Inagi,R., et.al., J. Am. Soc. Nephrol. 13 (11), 2715-2722 (2002)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Uniprot Description
SERPINB7: Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin. Belongs to the serpin family. Ov-serpin subfamily.
Chromosomal Location of Human Ortholog: 18q21.33
Cellular Component: extracellular space; cytoplasm
Molecular Function: serine-type endopeptidase inhibitor activity
Biological Process: positive regulation of transforming growth factor-beta1 production; positive regulation of collagen biosynthetic process
Disease: Palmoplantar Keratoderma, Nagashima Type
Research Articles on SERPINB7
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Product Notes
The SERPINB7 serpinb7 (Catalog #AAA9205424) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 108-137. The SERPINB7 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SERPINB7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the SERPINB7 serpinb7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SERPINB7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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