Rabbit SEC23IP Polyclonal Antibody | anti-SEC23IP antibody

SEC23IP Rabbit Polyclonal

Cat. Num. AAA7603913

• Gene Names: SEC23IP; P125; P125A; MSTP053
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: SEC23IP; Polyclonal Antibody; SEC23IP Rabbit Polyclonal; anti-SEC23IP antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 1000

• Applicable Applications for anti-SEC23IP antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Immunogen: SEC23 interacting protein
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human heart using MBS7603913 (SEC23IP antibody) at dilution of 1:50)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS7603913 (SEC23IP antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 6005824
• NCBI GeneID: 11196
• NCBI Accession #: NP_009121.1
• NCBI GenBank Nucleotide #: NM_007190.3
• Molecular Weight: 102,187 Da
• NCBI Official Full Name: SEC23-interacting protein
• NCBI Official Synonym Full Names: SEC23 interacting protein
• NCBI Official Symbol: SEC23IP
• NCBI Official Synonym Symbols: P125; P125A; MSTP053
• NCBI Protein Information: SEC23-interacting protein
• UniProt Protein Name: SEC23-interacting protein
• Protein Family: SEC23-interacting protein
• UniProt Gene Name: SEC23IP
• UniProt Entry Name: S23IP_HUMAN

NCBI Description

This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

Uniprot Description

SEC23IP: Plays a role in the organization of endoplasmic reticulum exit sites. Belongs to the PA-PLA1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Endoplasmic reticulum; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10q25-q26

Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; ER to Golgi transport vesicle; ER-Golgi intermediate compartment; Golgi membrane

Molecular Function: metal ion binding; protein binding

Biological Process: COPII coating of Golgi vesicle; Golgi organization and biogenesis; intracellular protein transport