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Immunohistochemistry (IHC) (Anti-SDR/SDPR antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Rabbit anti-Human SDR/SDPR Polyclonal Antibody | anti-SDR/SDPR antibody

Anti-SDR/SDPR Antibody (C-Terminus)

Gene Names
CAVIN2; SDR; SDPR; PS-p68; cavin-2
Reactivity
Human
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
SDR/SDPR; Polyclonal Antibody; Anti-SDR/SDPR Antibody (C-Terminus); Goat Polyclonal (IgG) to Human SDR/SDPR; SDPR; Cavin-2; CAVIN2; PS-p68; SDR; Serum deprivation response; anti-SDR/SDPR antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
This antibody is specific towards Cavin 2 SDR.
Purity/Purification
Immunoaffinity Purified
Form/Format
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 50% glycerol, sterile filtered
Sequence Length
425
Applicable Applications for anti-SDR/SDPR antibody
ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
ELISA: 1:20000-1:60000
IF: 1:100-1:500
IHC-P: 5 ug/ml
WB: 1 ug/ml
Immunogen
SDPR affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminal region of human SDPR.
Conjugation
Unconjugated
Epitope
C-Terminus
Preparation and Storage
Short term storage: 4 degree C
Long term storage: aliquot and store at -20 degree C, avoid freeze thaw cycles.
Centrifuge product before removing cap. Only dilute immediately prior to use.

Immunohistochemistry (IHC)

(Anti-SDR/SDPR antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-SDR/SDPR antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Related Product Information for anti-SDR/SDPR antibody
SDR/SDPR is a calcium-independent phospholipid-binding protein whoseexpression increases in serum-starved cells. This protein is a substratefor protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of This protein causes caveolae loss and its over-expression results in caveolaedeformation and membrane tubulation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,173 Da
NCBI Official Full Name
caveolae-associated protein 2
NCBI Official Synonym Full Names
caveolae associated protein 2
NCBI Official Symbol
CAVIN2
NCBI Official Synonym Symbols
SDR; SDPR; PS-p68; cavin-2
NCBI Protein Information
caveolae-associated protein 2
UniProt Protein Name
Caveolae-associated protein 2
UniProt Gene Name
CAVIN2

NCBI Description

This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]

Uniprot Description

Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae (PubMed:19525939). Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae ().

Research Articles on SDR/SDPR

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Product Notes

The SDR/SDPR cavin2 (Catalog #AAA2401000) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SDR/SDPR Antibody (C-Terminus) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SDR/SDPR can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ELISA: 1:20000-1:60000 IF: 1:100-1:500 IHC-P: 5 ug/ml WB: 1 ug/ml. Researchers should empirically determine the suitability of the SDR/SDPR cavin2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SDR/SDPR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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