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Western Blot (WB) (Western blot analysis of SDR Antibody (Center) in CHO cell line lysates (35ug/lane). SDR (arrow) was detected using the purified Pab.)

Rabbit SDR Polyclonal Antibody | anti-SDPR antibody

SDR Antibody (Center)

Gene Names
SDPR; SDR; CAVIN2; PS-p68; cavin-2
Reactivity
Human, hamster
Applications
Western Blot, ELISA, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
SDR; Polyclonal Antibody; SDR Antibody (Center); Serum deprivation-response protein; Cavin-2; PS-p68; Phosphatidylserine-binding protein; SDPR {ECO:0000312|EMBL:AAD177951}; anti-SDPR antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, hamster
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SDR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-135 amino acids from the Central region of human SDR.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
109-135
Sequence Length
425
Applicable Applications for anti-SDPR antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of SDR Antibody (Center) in CHO cell line lysates (35ug/lane). SDR (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of SDR Antibody (Center) in CHO cell line lysates (35ug/lane). SDR (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(SDR Antibody (Center) IHC analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SDR Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (SDR Antibody (Center) IHC analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SDR Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(SDR Antibody (Center) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (SDR Antibody (Center) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-SDPR antibody
This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.
Product Categories/Family for anti-SDPR antibody
References
Baig, A., et al. Proteomics 9(17):4254-4258(2009)
Hansen, C.G., et al. Nat. Cell Biol. 11(7):807-814(2009)
Ogata, T., et al. Mol. Cell. Biol. 28(10):3424-3436(2008)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47173
NCBI Official Full Name
serum deprivation-response protein
NCBI Official Synonym Full Names
serum deprivation response
NCBI Official Symbol
SDPR
NCBI Official Synonym Symbols
SDR; CAVIN2; PS-p68; cavin-2
NCBI Protein Information
serum deprivation-response protein
UniProt Protein Name
Serum deprivation-response protein
UniProt Gene Name
SDPR
UniProt Entry Name
SDPR_HUMAN

NCBI Description

This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]

Uniprot Description

SDPR: May play a role in targeting PRKCA to caveolae. Belongs to the PTRF/SDPR family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2q32-q33

Cellular Component: cytoplasm; caveola; cytosol

Molecular Function: protein binding; protein kinase C binding; phosphatidylserine binding; phospholipid binding

Research Articles on SDPR

Similar Products

Product Notes

The SDPR sdpr (Catalog #AAA9213793) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 109-135. The SDR Antibody (Center) reacts with Human, hamster and may cross-react with other species as described in the data sheet. AAA Biotech's SDR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the SDPR sdpr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SDR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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