Western Blot (WB)
(Western blot analysis of SDPR in HeLa cell lysate with SDPR antibody at (A) 1 and (B) 2 μg/mL)
Rabbit anti-Human SDPR Polyclonal Antibody | anti-SDPR antibody
SDPR Antibody
Gene Names
SDPR; SDR; CAVIN2; PS-p68; cavin-2
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
SDPR Antibody is affinity chromatography purified via peptide column.
Synonyms
SDPR; Polyclonal Antibody; SDPR Antibody; SDR; CAVIN2; PS-p68; cavin-2; Serum deprivation-response protein; Cavin-2; serum deprivation response; anti-SDPR antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
It is predicted to not cross-react with other members of the cavin family.
Purity/Purification
SDPR Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
425
Applicable Applications for anti-SDPR antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 mug/mL.
Conjugate
Unconjugated
Immunogen
Rabbit polyclonal SDPR antibody was raised against an 18 amino acid peptide near the amino terminus of human SDPR.
Buffer
SDPR Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
SDPR antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Western Blot (WB)
(Western blot analysis of SDPR in HeLa cell lysate with SDPR antibody at (A) 1 and (B) 2 μg/mL)
Western Blot (WB)
(Western blot analysis of SDPR in HeLa cell lysate with SDPR antibody at (A) 1 and (B) 2 μg/mL)
Immunohistochemistry (IHC)
(Immunohistochemistry of SDPR in human spleen tissue with SDPR antibody at 5 μg/ml.)
Immunohistochemistry (IHC)
(Immunohistochemistry of SDPR in human spleen tissue with SDPR antibody at 5 μg/ml.)
Immunofluorescence (IF)
(Immunofluorescence of SDPR in human spleen tissue with SDPR antibody at 20 μg/ml.)
Immunofluorescence (IF)
(Immunofluorescence of SDPR in human spleen tissue with SDPR antibody at 20 μg/ml.)
Related Product Information for anti-SDPR antibody
SDPR Antibody: The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47 kDa
NCBI Official Full Name
serum deprivation-response protein
NCBI Official Synonym Full Names
serum deprivation response
NCBI Official Symbol
SDPR
NCBI Official Synonym Symbols
SDR; CAVIN2; PS-p68; cavin-2
NCBI Protein Information
serum deprivation-response protein; SDPR; phosphatidylserine binding protein; phosphatidylserine-binding protein
UniProt Protein Name
Serum deprivation-response protein
Protein Family
UniProt Gene Name
SDPR
UniProt Entry Name
SDPR_HUMAN
NCBI Description
This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]
Uniprot Description
SDPR: May play a role in targeting PRKCA to caveolae. Belongs to the PTRF/SDPR family.
Protein type: Lipid-binding
Chromosomal Location of Human Ortholog: 2q32-q33
Cellular Component: cytoplasm; caveola; cytosol
Molecular Function: protein binding; protein kinase C binding; phosphatidylserine binding; phospholipid binding
Research Articles on SDPR
Similar Products
Product Notes
The SDPR sdpr (Catalog #AAA153503) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SDPR Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SDPR can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the SDPR sdpr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SDPR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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