Western Blot (WB)
(SCGB1D2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SCGB1D2 antibody detected the SCGB1D2 protein (arrow).)
Rabbit anti-Human SCGB1D2 Polyclonal Antibody | anti-SCGB1D2 antibody
SCGB1D2 Antibody (Center)
Western Blot (WB)
(SCGB1D2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SCGB1D2 antibody detected the SCGB1D2 protein (arrow).)
Western Blot (WB)
(SCGB1D2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SCGB1D2 antibody detected the SCGB1D2 protein (arrow).)
lipophilin subfamily, part of the uteroglobin superfamily, and is
an ortholog of prostatein, the major secretory glycoprotein of the
rat ventral prostate gland. Lipophilin gene products are widely
expressed in normal tissues, especially in endocrine-responsive
organs. Assuming that human lipophilins are the functional
counterparts of prostatein, they may be transcriptionally regulated
by steroid hormones, with the ability to bind androgens, other
steroids and possibly bind and concentrate estramustine, a
chemotherapeutic agent widely used for prostate cancer. Although
the gene has been reported to be on chromosome 10, this sequence
appears to be from a cluster of genes on chromosome 11 that
includes mammaglobin 2.
Culleton, J., et al. Int. J. Cancer 120(5):1087-1092(2007)
Sjodin, A., et al. Acta Neuropathol. 109(4):381-386(2005)
Carter, D., et al. Clin. Cancer Res. 9(2):749-754(2003)
Carter, D., et al. Biochemistry 41(21):6714-6722(2002)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008]
Uniprot Description
SCGB1D2: May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones. Belongs to the secretoglobin family. Lipophilin subfamily.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: extracellular space
Research Articles on SCGB1D2
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Product Notes
The SCGB1D2 scgb1d2 (Catalog #AAA9211015) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 22-50. The SCGB1D2 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SCGB1D2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SCGB1D2 scgb1d2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SCGB1D2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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