Rabbit SCGB1D2 Polyclonal Antibody | anti-SCGB1D2 antibody

SCGB1D2 Polyclonal Antibody

Cat. Num. AAA2527920

• Gene Names: SCGB1D2; LIPB; LPHB; LPNB
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: SCGB1D2; Polyclonal Antibody; SCGB1D2 Polyclonal Antibody; LIPB; LPHB; LPNB; anti-SCGB1D2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen affinity purification
• Concentration: 2.7mg/mL (varies by lot)
• Sequence Length: 90

• Applicable Applications for anti-SCGB1D2 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: IHC: 1:50-1:200
• Immunogen: Synthetic peptide of human SCGB1D2
• Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
• Preparation and Storage: Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using SCGB1D2 Polyclonal Antibody at dilution 1:40)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human brain tissue using SCGB1D2 Polyclonal Antibody at dilution 1:40)

Related Product Information for anti-SCGB1D2 antibody

The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2.

NCBI and Uniprot Product Information

• NCBI GI #: 5729909
• NCBI GeneID: 10647
• NCBI Accession #: NP_006542.1
• NCBI GenBank Nucleotide #: NM_006551.3
• Molecular Weight: 9,925 Da
• NCBI Official Full Name: secretoglobin family 1D member 2
• NCBI Official Synonym Full Names: secretoglobin, family 1D, member 2
• NCBI Official Symbol: SCGB1D2
• NCBI Official Synonym Symbols: LIPB; LPHB; LPNB
• NCBI Protein Information: secretoglobin family 1D member 2; lipophilin-B; prostatein-like lipophilin B
• UniProt Protein Name: Secretoglobin family 1D member 2
• Protein Family: Secretoglobin family
• UniProt Gene Name: SCGB1D2
• UniProt Synonym Gene Names: LIPHB; LPNB
• UniProt Entry Name: SG1D2_HUMAN

NCBI Description

The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008]

Uniprot Description

SCGB1D2: May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones. Belongs to the secretoglobin family. Lipophilin subfamily.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: extracellular space