Rabbit anti-Human SCGB1D2 Polyclonal Antibody | anti-SCGB1D2 antibody

SCGB1D2, ID (SCGB1D2, LIPHB, Secretoglobin family 1D member 2, Lipophilin-B) (PE)

Cat. Num. AAA6345293

• Gene Names: SCGB1D2; LIPB; LPHB; LPNB
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SCGB1D2; Polyclonal Antibody; ID (SCGB1D2; LIPHB; Secretoglobin family 1D member 2; Lipophilin-B) (PE); Lipophilin-B; anti-SCGB1D2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-SCGB1D2 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: SCGB1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the Central region of human SCGB1D2.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(SCGB1D2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SCGB1D2 antibody detected the SCGB1D2 protein (arrow).)

Related Product Information for anti-SCGB1D2 antibody

The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2.

Product Categories/Family for anti-SCGB1D2 antibody

Antibodies; Secretoglobin; Uteroglobin; CC16

References

Sjodin, A., et al. Anticancer Res. 28 (3A), 1493-1498 (2008): Culleton, J., et al. Int. J. Cancer 120(5):1087-1092(2007). Sjodin, A., et al. Acta Neuropathol. 109(4):381-386(2005). Carter, D., et al. Clin. Cancer Res. 9(2):749-754(2003). Carter, D., et al. Biochemistry 41(21):6714-6722(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 5729909
• NCBI GeneID: 10647
• NCBI Accession #: NP_006542.1
• NCBI GenBank Nucleotide #: NM_006551.3
• UniProt Accession #: O95969; Q2M3N9
• Molecular Weight: 9,925 Da
• NCBI Official Full Name: secretoglobin family 1D member 2
• NCBI Official Synonym Full Names: secretoglobin, family 1D member 2
• NCBI Official Symbol: SCGB1D2
• NCBI Official Synonym Symbols: LIPB; LPHB; LPNB
• NCBI Protein Information: secretoglobin family 1D member 2
• UniProt Protein Name: Secretoglobin family 1D member 2
• Protein Family: Secretoglobin family
• UniProt Gene Name: SCGB1D2
• UniProt Synonym Gene Names: LIPHB; LPNB

NCBI Description

The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008]

Uniprot Description

May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.