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Rabbit SARS-CoV-2 (2019-nCoV) Nucleocapsid Polyclonal Antibody | anti-NP-CoV antibody

SARS-CoV-2 (2019-nCoV) Nucleocapsid Antibody, Rabbit PAb, Antigen Affinity Purified

Reactivity
SARS-CoV-2
Applications
ELISA
Purity
Protein A & Antigen Affinity
Synonyms
SARS-CoV-2 (2019-nCoV) Nucleocapsid; Polyclonal Antibody; SARS-CoV-2 (2019-nCoV) Nucleocapsid Antibody; Rabbit PAb; Antigen Affinity Purified; anti-NP-CoV antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
SARS-CoV-2
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
SARS-CoV-2 (2019-nCoV) NP Protein
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid. 0.2um filtered solution in PBS
Applicable Applications for anti-NP-CoV antibody
ELISA (EIA)
Application Notes
ELISA: 1:5000-1:10,000
Antibody's applications haven't been validated with corresponding virus positive samples.
Immunogen
Recombinant SARS-CoV-2/2019-nCoV Nucleocapsid Protein
Conjugation
Unconjugated
Cross-reactivity
Has cross-reactivity in ELISA and WB with
SARS-CoV NP Protein
Preparation
Produced in rabbits immunized with purified, recombinant SARS-CoV-2/2019-nCoV Nucleocapsid Protein; Met1-Ala419). The specific IgG was purified by SARS-CoV-2/2019-nCoV Nucleocapsid affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Related Product Information for anti-NP-CoV antibody
Background: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The coronavirus N protein is required for coronavirus RNA synthesis and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is the most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to the formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of the N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a test tool.
References
1.Van Boheemen S, et al. (2012), MBio. 3(6):e00473-12. Bisht H. et al., 2004, Proc Natl Acad Sci. 101 (17): 6641-6. Li W. et al., 2005, Science. 309 (5742): 1864-8.

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Product Notes

The NP-CoV (Catalog #AAA8119532) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SARS-CoV-2 (2019-nCoV) Nucleocapsid Antibody, Rabbit PAb, Antigen Affinity Purified reacts with SARS-CoV-2 and may cross-react with other species as described in the data sheet. AAA Biotech's SARS-CoV-2 (2019-nCoV) Nucleocapsid can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:5000-1:10,000 Antibody's applications haven't been validated with corresponding virus positive samples. Researchers should empirically determine the suitability of the NP-CoV for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SARS-CoV-2 (2019-nCoV) Nucleocapsid, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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