Western Blot (WB)
(Western blot analysis RIP3 (Phospho- Ser316) using EGF treated MCF7 whole cell lysates)
Rabbit RIP3 Polyclonal Antibody | anti-RIP3 antibody
RIP3 (Phospho-Ser316) Antibody
Gene Names
Ripk3; Rip3; AW107945; 2610528K09Rik
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Synonyms
RIP3; Polyclonal Antibody; RIP3 (Phospho-Ser316) Antibody; Receptor interacting protein 3 antibody; anti-RIP3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Phospho-RIP3 (S316) Antibody detects endogenous levels of RIP3 only when phosphorylated at S316
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+) pH 7.4 150mM NaCl 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
486
Applicable Applications for anti-RIP3 antibody
Western Blot (WB)
Application Notes
WB: 1:1000
Immunogen
A synthesized peptide derived from human RIP3 (Phospho- Ser316)
Immunogen Type
Peptide-KLH
Preparation and Storage
Store at -20 degree C.
Western Blot (WB)
(Western blot analysis RIP3 (Phospho- Ser316) using EGF treated MCF7 whole cell lysates)
Western Blot (WB)
(Western blot analysis RIP3 (Phospho- Ser316) using EGF treated MCF7 whole cell lysates)
Product Categories/Family for anti-RIP3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46-62
NCBI Official Full Name
receptor-interacting serine/threonine-protein kinase 3 isoform 1
NCBI Official Synonym Full Names
receptor-interacting serine-threonine kinase 3
NCBI Official Symbol
Ripk3
NCBI Official Synonym Symbols
Rip3; AW107945; 2610528K09Rik
NCBI Protein Information
receptor-interacting serine/threonine-protein kinase 3
UniProt Protein Name
Receptor-interacting serine/threonine-protein kinase 3
Protein Family
UniProt Gene Name
Ripk3
UniProt Synonym Gene Names
Rip3; RIP-3; mRIP3
Uniprot Description
Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.
Research Articles on RIP3
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Product Notes
The RIP3 ripk3 (Catalog #AAA9428992) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RIP3 (Phospho-Ser316) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RIP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000. Researchers should empirically determine the suitability of the RIP3 ripk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RIP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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