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VAP-1/AOC3 Protein Recombinant Protein | VAP-1/AOC3 recombinant protein
Recombinant Human VAP-1/AOC3 Protein (His Tag)
Purity
> 95 % as determined by reducing SDS-PAGE.
Synonyms
VAP-1/AOC3 Protein; Recombinant Human VAP-1/AOC3 Protein (His Tag); Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazidesensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1; AOC3; VAP1; VAP-1/AOC3 recombinant protein
Host
Human Cells
Purity/Purification
> 95 % as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 ?m filtered solution of 20mM Tris, 500mM NaCl, pH8.0.
Sequence
Arg27-Asn763
Tag Information
C-6His
Endotoxin
< 1.0 EU per ?g as determined by the LAL method.
Preparation and Storage
Store at < -20 degree C, stable for 6 months. Please minimize freeze-thaw cycles.
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Related Product Information for VAP-1/AOC3 recombinant protein
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases in diabetes and some inflammatory liver diseases. VAP-1 catalyzes the oxidative deamination of small primary amines such as methylamine, benzylamine, and aminoacetone in a reaction that produces an aldehyde, ammonia, and H2O2. VAP-1 vascular expression is regulated at sites of inflammation through its release from intracellular granules in which the protein is stored. The adhesive function of VAP-1 has been demonstrated in studies showing that the protein is important for the adherence of certain lymphocyte subtypes to inflamed endothelial tissues. VAP-1 mediated adhesion is involved in the process of leukocyte extravasation, an important feature of inflammatory responses. VAP-1 is considered to be a therapeutic target for diabetes, oxidative stress, and inflammatory diseases.
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
Mol_Mass 82.6 kDa; AP_Mol_Mass 64 kDa
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Product Notes
The VAP-1/AOC3 (Catalog #AAA2552952) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is C-6His. The amino acid sequence is listed below: Arg27-Asn7 63. It is sometimes possible for the material contained within the vial of "VAP-1/AOC3 Protein, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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