Western Blot (WB)
(All lanes: DNA repair protein RAD51 homolog 4 antibody at 8ug/ml+Jurkat whole cell lysate)
Rabbit anti-Human RAD51D Polyclonal Antibody | anti-RAD51D antibody
RAD51D Polyclonal Antibody
Immunohistochemistry: 1:20 - 1:200
Western Blot (WB)
(All lanes: DNA repair protein RAD51 homolog 4 antibody at 8ug/ml+Jurkat whole cell lysate)
Western Blot (WB)
(All lanes: DNA repair protein RAD51 homolog 4 antibody at 8ug/ml+Jurkat whole cell lysate)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded humanprostate cancer using at dilution of 1:100.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded humanprostate cancer using at dilution of 1:100.)
NCBI and Uniprot Product Information
Uniprot Description
RAD51L3: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Defects in RAD51D are a cause of susceptibility to familial breast-ovarian cancer type 4 (BROVCA4). A condition associated with familial predisposition to cancer of the breast and ovaries. Characteristic features in affected families are an early age of onset of breast cancer (often before age 50), increased chance of bilateral cancers (cancer that develop in both breasts, or both ovaries, independently), frequent occurrence of breast cancer among men, increased incidence of tumors of other specific organs, such as the prostate. Belongs to the RecA family. RAD51 subfamily. 8 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 17q11
Cellular Component: centrosome; chromosome, telomeric region; nuclear chromosome, telomeric region; nucleoplasm; nucleus; replication fork
Molecular Function: DNA binding; DNA-dependent ATPase activity; double-stranded DNA binding; endodeoxyribonuclease activity; four-way junction DNA binding; gamma-tubulin binding; protein binding; recombinase activity; single-stranded DNA binding
Biological Process: DNA repair; DNA synthesis during DNA repair; double-strand break repair via homologous recombination; meiotic DNA recombinase assembly; meiotic recombination; mitotic recombination; response to ionizing radiation; strand displacement; strand invasion; telomere maintenance
Disease: Breast-ovarian Cancer, Familial, Susceptibility To, 4
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Product Notes
The RAD51D rad51d (Catalog #AAA9415377) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAD51D Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RAD51D can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500 - 1:1000 Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the RAD51D rad51d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAD51D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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