Immunohistochemistry (IHC)
(Human Uterus, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human IL11 Polyclonal Antibody | anti-IL11 antibody
Anti-IL11 Antibody
IHC-P: 10 ug/ml
Store at -20 degree C and it will be stable for up to one year.
Avoid repeated freeze thaw cycles.
Immunohistochemistry (IHC)
(Human Uterus, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Uterus, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (WB)
(Human Skin, Dermal Capillaries: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (WB)
(Human Skin, Dermal Capillaries: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunocytochemistry (ICC)
(Immunocytochemistry of IL-11 in HeLa cells with IL-11 antibody at 10 ug/ml.)
Immunocytochemistry (ICC)
(Immunocytochemistry of IL-11 in HeLa cells with IL-11 antibody at 10 ug/ml.)
Immunofluorescence (IF)
(Immunofluorescence of IL-11 in HeLa cells with IL-11 antibody at 20 ug/ml.)
Immunofluorescence (IF)
(Immunofluorescence of IL-11 in HeLa cells with IL-11 antibody at 20 ug/ml.)
Western Blot (WB)
(Western blot analysis of IL-11 in Hela Cell lysate with IL-11 antibody at 1 ug/ml.)
Western Blot (WB)
(Western blot analysis of IL-11 in Hela Cell lysate with IL-11 antibody at 1 ug/ml.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Uniprot Description
Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
Research Articles on IL11
Similar Products
Product Notes
The IL11 il11 (Catalog #AAA2401413) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IL11 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ICC: 10 ug/ml IHC-P: 10 ug/ml. Researchers should empirically determine the suitability of the IL11 il11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
