Western Blot (WB)
(PSMB11 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PSMB11 antibody detected the PSMB11 protein (arrow).)
Rabbit anti-Human PSMB11 Polyclonal Antibody | anti-Psmb11 antibody
PSMB11, CT (PSMB11, Proteasome subunit beta type-11, Proteasome subunit beta-5t)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Western Blot (WB)
(PSMB11 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PSMB11 antibody detected the PSMB11 protein (arrow).)
Western Blot (WB)
(PSMB11 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PSMB11 antibody detected the PSMB11 protein (arrow).)
Immunohistochemistry (IHC)
(PSMB11 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human thymoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PSMB11 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(PSMB11 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human thymoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PSMB11 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
Uniprot Description
Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Incorporated instead of PSMB5 or PSMB8, this unit reduces the chymotrypsin-like activity of the proteasome. Plays a pivotal role in development of CD8-positive T-cells. Ref.1
Catalytic activity: Cleavage of peptide bonds with very broad specificity.
Subunit structure: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. Incorporated instead of PSMB5 and PSMB8. Ref.1
Subcellular location: Cytoplasm
By similarity. Nucleus
By similarity.
Tissue specificity: Expressed exclusively in cortical thymic epithelial cells. Ref.1
Disruption phenotype: Displays defective development of CD8-positive T-cells in the thymus. Ref.1
Sequence similarities: Belongs to the peptidase T1B family.
Research Articles on Psmb11
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Product Notes
The Psmb11 psmb11 (Catalog #AAA647537) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PSMB11, CT (PSMB11, Proteasome subunit beta type-11, Proteasome subunit beta-5t) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PSMB11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100. Researchers should empirically determine the suitability of the Psmb11 psmb11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSMB11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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