Chicken Proteasome 26S Non-ATPase Subunit 8 Polyclonal Antibody | anti-PSMD8 antibody

Proteasome 26S Non-ATPase Subunit 8 (PSMD8, 26S Proteasome Regulatory Subunit p31)

Cat. Num. AAA616211

• Gene Names: PSMD8; p31; MGC127792
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: Proteasome 26S Non-ATPase Subunit 8; Polyclonal Antibody; Proteasome 26S Non-ATPase Subunit 8 (PSMD8; 26S Proteasome Regulatory Subunit p31); Anti -Proteasome 26S Non-ATPase Subunit 8 (PSMD8; anti-PSMD8 antibody

• Host: Chicken
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgY
• Specificity: Recognizes human Proteasome 26S Non-ATPase Subunit 8. Species Crossreactivity: Mouse and rat.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.

• Applicable Applications for anti-PSMD8 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.; Dilution: Western Blot: 1:1000-1:2000
• Immunogen: Synthetic peptide corresponding to aa1-257
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Western Blot (WB)

(Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development)

Related Product Information for anti-PSMD8 antibody

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The gene encoding this protein encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.

Product Categories/Family for anti-PSMD8 antibody

Antibodies; Abs to Proteasomes

NCBI and Uniprot Product Information

• NCBI GI #: 78042570
• NCBI GeneID: 512891
• NCBI Accession #: NP_001030283.1
• NCBI GenBank Nucleotide #: NM_001035111.1
• UniProt Accession #: Q3SYT7; Q9TRA6
• Molecular Weight: 32,538 Da
• NCBI Official Full Name: 26S proteasome non-ATPase regulatory subunit 8
• NCBI Official Symbol: PSMD8
• NCBI Official Synonym Symbols: p31; MGC127792
• NCBI Protein Information: 26S proteasome non-ATPase regulatory subunit 8; proteasome 26S non-ATPase subunit 8; 26S proteasome regulatory subunit S14; 26S proteasome regulatory subunit RPN12
• UniProt Protein Name: 26S proteasome non-ATPase regulatory subunit 8
• Protein Family: 26S proteasome non-ATPase regulatory
• UniProt Gene Name: PSMD8
• UniProt Entry Name: PSMD8_BOVIN

Uniprot Description

Function: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase

Sequence similarities: Belongs to the proteasome subunit S14 family.