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anti-Mouse Protease Nexin 1 antiserum Polyclonal Antibody | anti-SERPINE2 antibody

Sheep anti mouse Protease Nexin 1 antiserum

Gene Names
Serpine2; PI7; PI-7; PN-1; Spi4; PAI-1; B230326M24Rik
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Serum
Synonyms
Protease Nexin 1 antiserum; Polyclonal Antibody; Sheep anti mouse Protease Nexin 1 antiserum; anti-SERPINE2 antibody
Ordering
For Research Use Only!
Host
Host: Sheep; Source: Sheep serum
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Serum
Form/Format
Frozen liquid
Concentration
Whole Antiserum (varies by lot)
Sequence Length
397
Applicable Applications for anti-SERPINE2 antibody
ELISA (EIA), Western Blot (WB)
Immunogen
Recombinant full length wild-type mouse protein (Glycosylated).
Target Information
Recognises Protease Nexin 1
Target Molecular Weight
47000
Preparation and Storage
Store at -70 degree C. Shelf Life: 5 years from delivery
Related Product Information for anti-SERPINE2 antibody
Polyclonal antiserum (host sheep).
Product Categories/Family for anti-SERPINE2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,207 Da
NCBI Official Full Name
glia-derived nexin
NCBI Official Synonym Full Names
serine (or cysteine) peptidase inhibitor, clade E, member 2
NCBI Official Symbol
Serpine2
NCBI Official Synonym Symbols
PI7; PI-7; PN-1; Spi4; PAI-1; B230326M24Rik
NCBI Protein Information
glia-derived nexin; GDN; serpin E2; protease nexin 1; protease nexin I; peptidase inhibitor 7; serine protease inhibitor 4; serine protease-inhibitor 4; serine (or cysteine) proteinase inhibitor, clade E, member 2; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
UniProt Protein Name
Glia-derived nexin
Protein Family
UniProt Gene Name
Serpine2
UniProt Synonym Gene Names
Pi7; Pn1; Spi4; GDN; PI-7; PN-1
UniProt Entry Name
GDN_MOUSE

Uniprot Description

SERPINE2: Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin. Belongs to the serpin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Inhibitor; Secreted, signal peptide

Cellular Component: extracellular matrix; extracellular space; extrinsic to external side of plasma membrane; membrane; cell soma; cell; extracellular region; cytosol; neuromuscular junction; vesicle

Molecular Function: heparin binding; serine-type endopeptidase inhibitor activity; glycosaminoglycan binding; protease inhibitor activity; receptor binding

Biological Process: negative regulation of proteolysis; nervous system development; regulation of synaptic transmission, glutamatergic; secretory granule organization and biogenesis; multicellular organismal development; cerebellar granular layer morphogenesis; negative regulation of blood coagulation; negative regulation of peptidase activity; mating plug formation; detection of mechanical stimulus involved in sensory perception; negative regulation of cell proliferation; negative regulation of smoothened signaling pathway; response to wounding; negative regulation of cell growth; blood coagulation; cell differentiation; negative regulation of protein catabolic process; regulation of timing of cell differentiation; negative regulation of phosphoinositide 3-kinase cascade; secretion by cell; positive regulation of astrocyte differentiation

Research Articles on SERPINE2

Similar Products

Product Notes

The SERPINE2 serpine2 (Catalog #AAA135180) is an Antibody produced from Host: Sheep; Source: Sheep serum and is intended for research purposes only. The product is available for immediate purchase. The Sheep anti mouse Protease Nexin 1 antiserum reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Protease Nexin 1 antiserum can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the SERPINE2 serpine2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Protease Nexin 1 antiserum, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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