Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug A172 cell Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 30 seconds)
Rabbit anti-Human PPP2R3A Polyclonal Antibody | anti-PPP2R3A antibody
PPP2R3A Antibody
Immunohistochemistry: 1:50-1:200
Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug A172 cell Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 30 seconds)
Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug A172 cell Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 30 seconds)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Jun 2010]
Uniprot Description
PPP2R3A: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit
Chromosomal Location of Human Ortholog: 3q22.1
Cellular Component: protein phosphatase type 2A complex
Molecular Function: protein binding; protein phosphatase type 2A regulator activity; calcium ion binding
Biological Process: regulation of catalytic activity; positive regulation of protein catabolic process; protein amino acid dephosphorylation; eye photoreceptor cell differentiation; somatic muscle development
Research Articles on PPP2R3A
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Product Notes
The PPP2R3A ppp2r3a (Catalog #AAA9407827) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPP2R3A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPP2R3A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:200-1:1000 Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the PPP2R3A ppp2r3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPP2R3A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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