Rabbit anti-Human PPP2R3A Polyclonal Antibody | anti-PPP2R3A antibody

PPP2R3A Rabbit Polyclonal

Cat. Num. AAA7602952

• Gene Names: PPP2R3A; PR72; PR130; PPP2R3
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: PPP2R3A; Polyclonal Antibody; PPP2R3A Rabbit Polyclonal; anti-PPP2R3A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 263

• Applicable Applications for anti-PPP2R3A antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: Protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain using MBS7602952 (PPP2R3A antibody) at dilution of 1:100)

Western Blot (WB)

(PC-3 cells were subjected to SDS PAGE followed by western blot with MBS7602952 (PPP2R3A antibody) at dilution of 1:300)

NCBI and Uniprot Product Information

• NCBI GI #: 118600852
• NCBI GeneID: 5523
• Molecular Weight: 48,178 Da
• NCBI Official Full Name: PPP2R3A protein, partial
• NCBI Official Synonym Full Names: protein phosphatase 2 regulatory subunit B''alpha
• NCBI Official Symbol: PPP2R3A
• NCBI Official Synonym Symbols: PR72; PR130; PPP2R3
• NCBI Protein Information: serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
• UniProt Protein Name: Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
• Protein Family: Serine/threonine-protein phosphatase
• UniProt Gene Name: PPP2R3A
• UniProt Synonym Gene Names: PPP2R3
• UniProt Entry Name: P2R3A_HUMAN

NCBI Description

This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Jun 2010]

Uniprot Description

PPP2R3A: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: protein phosphatase type 2A complex

Molecular Function: calcium ion binding; protein binding; protein binding, bridging; protein phosphatase type 2A regulator activity

Biological Process: eye photoreceptor cell differentiation; positive regulation of protein catabolic process; protein amino acid dephosphorylation; regulation of protein phosphatase type 2A activity; somatic muscle development