Western Blot (WB)
(PNKD Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PNKD antibody detected the PNKD protein (arrow).)
Rabbit anti-Mouse PNKD Polyclonal Antibody | anti-PNKD antibody
PNKD, NT (PNKD, KIAA1184, MR1, TAHCCP2, Probable hydrolase PNKD, Myofibrillogenesis regulator 1, Paroxysmal nonkinesiogenic dyskinesia protein, Trans-activated by hepatitis C virus core protein 2) (FITC)
Gene Names
PNKD; MR1; PDC; DYT8; FPD1; MR-1; BRP17; PKND1; PNKD1; FKSG19; TAHCCP2; KIPP1184
Reactivity
Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PNKD; Polyclonal Antibody; NT (PNKD; KIAA1184; MR1; TAHCCP2; Probable hydrolase PNKD; Myofibrillogenesis regulator 1; Paroxysmal nonkinesiogenic dyskinesia protein; Trans-activated by hepatitis C virus core protein 2) (FITC); Trans-activated by hepatitis C virus core protein 2; anti-PNKD antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-PNKD antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
PNKD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human PNKD.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(PNKD Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PNKD antibody detected the PNKD protein (arrow).)
Western Blot (WB)
(PNKD Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PNKD antibody detected the PNKD protein (arrow).)
Immunohistochemistry (IHC)
(PNKD Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PNKD Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(PNKD Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PNKD Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-PNKD antibody
This gene is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non-kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-PNKD antibody
References
Yang, J., et al. Neuron 66(6):871-883(2010). Davila, S., et al. Genes Immun. 11(3):232-238(2010). Ghezzi, D., et al. Hum. Mol. Genet. 18(6):1058-1064(2009). Friedman, A., et al. Eur. Neurol. 61(1):39-41(2009). Ren, K., et al. J. Biol. Chem. 283(51):35598-35605(2008).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,849 Da
NCBI Official Full Name
probable hydrolase PNKD isoform 3
NCBI Official Synonym Full Names
paroxysmal nonkinesigenic dyskinesia
NCBI Official Symbol
PNKD
NCBI Official Synonym Symbols
MR1; PDC; DYT8; FPD1; MR-1; BRP17; PKND1; PNKD1; FKSG19; TAHCCP2; KIPP1184
NCBI Protein Information
probable hydrolase PNKD
UniProt Protein Name
Probable hydrolase PNKD
Protein Family
UniProt Gene Name
PNKD
UniProt Synonym Gene Names
KIAA1184; MR1; TAHCCP2; MR-1
NCBI Description
This gene is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non-kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Uniprot Description
Probable hydrolase that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa-B signaling pathway.
Research Articles on PNKD
Similar Products
Product Notes
The PNKD pnkd (Catalog #AAA6335260) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PNKD, NT (PNKD, KIAA1184, MR1, TAHCCP2, Probable hydrolase PNKD, Myofibrillogenesis regulator 1, Paroxysmal nonkinesiogenic dyskinesia protein, Trans-activated by hepatitis C virus core protein 2) (FITC) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PNKD can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PNKD pnkd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PNKD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
