Western Blot (WB)
(Western blot analysis of SYNPO2L in human thymus tissue lysate with SYNPO2L antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Rabbit anti-Human, Mouse SYNPO2L Polyclonal Antibody | anti-SYNPO2L antibody
SYNPO2L Antibody
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunocytochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
SYNPO2L; Polyclonal Antibody; SYNPO2L Antibody; Synaptopodin 2-like; cytoskeletal heart-enriched actin-associated protein; CHAP; anti-SYNPO2L antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
977
Applicable Applications for anti-SYNPO2L antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 19 amino acid peptide near the amino terminus of human SYNPO2L.
Target Name
SYNPO2L
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of SYNPO2L in human thymus tissue lysate with SYNPO2L antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of SYNPO2L in human thymus tissue lysate with SYNPO2L antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Immunohistochemistry (IHC)
(Immunohistochemistry of SYNPO2L in mouse skeletal muscle tissue with SYNPO2L antibody at 5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of SYNPO2L in mouse skeletal muscle tissue with SYNPO2L antibody at 5 ug/mL.)
Related Product Information for anti-SYNPO2L antibody
SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.
Product Categories/Family for anti-SYNPO2L antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
79,146 Da
NCBI Official Full Name
synaptopodin 2-like
UniProt Protein Name
Synaptopodin 2-like protein
Protein Family
UniProt Gene Name
SYNPO2L
UniProt Entry Name
SYP2L_HUMAN
Uniprot Description
SYNPO2L: Actin-associated protein that may play a role in modulating actin-based shape. Belongs to the synaptopodin family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 10q22.2
Cellular Component: cytoskeleton; Z disc; nucleus
Molecular Function: actin binding
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Product Notes
The SYNPO2L synpo2l (Catalog #AAA9408531) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYNPO2L Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SYNPO2L can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the SYNPO2L synpo2l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYNPO2L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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