Rabbit anti-Human PLEKHM2 Polyclonal Antibody | anti-PLEKHM2 antibody

PLEKHM2, CT (Pleckstrin Homology Domain-containing Family M Member 2, PH Domain-containing Family M Member 2, Salmonella-induced Filaments A and Kinesin-interacting Protein, SifA and Kinesin-interacting Protein, KIAA0842, SKIP)

Cat. Num. AAA6013239

• Gene Names: PLEKHM2; SKIP; RP11-169K16.1
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: PLEKHM2; Polyclonal Antibody; CT (Pleckstrin Homology Domain-containing Family M Member 2; PH Domain-containing Family M Member 2; Salmonella-induced Filaments A and Kinesin-interacting Protein; SifA and Kinesin-interacting Protein; KIAA0842; SKIP); Anti -PLEKHM2; anti-PLEKHM2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human PLEKHM2. Species sequence homology: Mouse, rat.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.02% sodium azide.

• Applicable Applications for anti-PLEKHM2 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot and Immunohistochemistry.; Dilution: Western Blot: 0.5-1ug/ml; Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
• Immunogen: Synthetic peptide corresponding to human PLEKHM2 at C-terminal conjugated to KLH.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Skeletal Muscle: Formalin -Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot analysis of PLEKHM2 in rat brain tissue lysate with PLEKHM2 antibody at 0.5ug/ml in (A) the absence and (B) the presence of blocking peptide. Below: Immunohistochemistry of FAM59A in human liver tissue with FAM59A antibody at 5ug/ml.)

Related Product Information for anti-PLEKHM2 antibody

May play a role in the regulation of conventional kinesin activity. Required for maintenance of the Golgi apparatus organization. May play a role in membrane tubulation.

Product Categories/Family for anti-PLEKHM2 antibody

Antibodies; Abs to Pleckstrin Homology Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 27469577
• NCBI GeneID: 23207
• UniProt Accession #: Q8IWE5; O94928; Q5VT65; Q6NUH9; Q7L8G1; Q8IVT7; Q8N2T4; Q96AY0; Q9NTF7
• Molecular Weight: 112,780 Da
• NCBI Official Full Name: PLEKHM2 protein, partial
• NCBI Official Synonym Full Names: pleckstrin homology domain containing, family M (with RUN domain) member 2
• NCBI Official Symbol: PLEKHM2
• NCBI Official Synonym Symbols: SKIP; RP11-169K16.1
• NCBI Protein Information: pleckstrin homology domain-containing family M member 2; sifA and kinesin-interacting protein; PH domain-containing family M member 2; novel RUN and PH domain-containing protein; salmonella-induced filaments A and kinesin-interacting protein; SifA (Salmonella-induced filaments A) and kinesin-interacting protein
• UniProt Protein Name: Pleckstrin homology domain-containing family M member 2
• Protein Family: Pleckstrin homology domain-containing family
• UniProt Gene Name: PLEKHM2
• UniProt Synonym Gene Names: KIAA0842; SKIP; PH domain-containing family M member 2
• UniProt Entry Name: PKHM2_HUMAN

Uniprot Description

PLEKHM2: May play a role in the regulation of conventional kinesin activity. Required for maintenance of the Golgi apparatus organization. May play a role in membrane tubulation.

Chromosomal Location of Human Ortholog: 1p36.21

Cellular Component: cytoplasm

Molecular Function: protein binding; kinesin binding

Biological Process: Golgi organization and biogenesis