Western Blot (WB)
(WB Suggested Anti-PINX1 Antibody Titration: 0.2-1 ug/mlPositive Control: COLO205 cell lysate)
Rabbit PINX1 Polyclonal Antibody | anti-PINX1 antibody
PINX1 antibody - N-terminal region
Gene Names
PINX1; Gno1; LPTL; LPTS; Pxr1
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Applications
Western Blot
Purity
Affinity Purified
Synonyms
PINX1; Polyclonal Antibody; PINX1 antibody - N-terminal region; anti-PINX1 antibody
Host
Rabbit
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: EKMGWSKGKGLGAQEQGATDHIKVQVKNNHLGLGATINNEDNWIAHQDDF
Sequence Length
328
Applicable Applications for anti-PINX1 antibody
Western Blot (WB)
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human PINX1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(WB Suggested Anti-PINX1 Antibody Titration: 0.2-1 ug/mlPositive Control: COLO205 cell lysate)
Western Blot (WB)
(WB Suggested Anti-PINX1 Antibody Titration: 0.2-1 ug/mlPositive Control: COLO205 cell lysate)
Related Product Information for anti-PINX1 antibody
This is a rabbit polyclonal antibody against PINX1. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. PINX1 mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. PINX1 inhibits telomerase activity and may inhibit cell proliferation and
Target Description: PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. PINX1 mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. PINX1 inhibits telomerase activity and may inhibit cell proliferation and
Product Categories/Family for anti-PINX1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37kDa
NCBI Official Full Name
PIN2/TERF1-interacting telomerase inhibitor 1 isoform 1
NCBI Official Synonym Full Names
PIN2 (TERF1) interacting telomerase inhibitor 1
NCBI Official Symbol
PINX1
NCBI Official Synonym Symbols
Gno1; LPTL; LPTS; Pxr1
NCBI Protein Information
PIN2/TERF1-interacting telomerase inhibitor 1
UniProt Protein Name
PIN2/TERF1-interacting telomerase inhibitor 1
Protein Family
UniProt Gene Name
PINX1
UniProt Synonym Gene Names
LPTL; LPTS
UniProt Entry Name
PINX1_HUMAN
Uniprot Description
PINX1: Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor. Belongs to the PINX1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Tumor suppressor; Inhibitor; Nucleolus
Chromosomal Location of Human Ortholog: 8p23
Cellular Component: nucleoplasm; kinetochore; nuclear chromosome; chromosome, telomeric region; mitochondrion; intracellular membrane-bound organelle; cytoplasm; nucleolus; spindle; nucleus
Molecular Function: protein binding
Biological Process: negative regulation of cell proliferation; negative regulation of telomerase activity; regulation of telomerase activity; telomere maintenance via telomerase; mitotic metaphase plate congression
Research Articles on PINX1
Similar Products
Product Notes
The PINX1 pinx1 (Catalog #AAA3213150) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PINX1 antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PINX1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the PINX1 pinx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: EKMGWSKGKG LGAQEQGATD HIKVQVKNNH LGLGATINNE DNWIAHQDDF. It is sometimes possible for the material contained within the vial of "PINX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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