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Immunohistochemistry (IHC) (Anti-PILRB antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.)

Goat anti-Human PILRB Polyclonal Antibody | anti-PILRB antibody

Goat Polyclonal to Human PILRB

Gene Names
PILRB; FDFACT1; FDFACT2
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Immunoaffinity Purified
Synonyms
PILRB; Polyclonal Antibody; Goat Polyclonal to Human PILRB; Anti-PILRB Antibody IHC-plus; Activating receptor PILR-beta; Activating receptor PILRbeta; Cell surface receptor FDFACT; Cell surface receptor FDFACT1; Cell surface receptor FDFACT2; FDFACT2; FDFACT1; FDFACT; Human PILRB; anti-PILRB antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Specificity
Human PILRB. Both variants represent identical proteins (NP_038468.3; NP_839956.1). This antibody is expected to recognize isoform a only (NP_038468.3; NP_839956.1).
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
271
Applicable Applications for anti-PILRB antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes
ELISA, IHC-P (3 - 6 ug/ml)
Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH...
Target Species
Human
Immunogen Description
Synthetic peptide C-RVTESKGHSESWH from an internal region of human PILRB (NP_038468.3; NP_839956.1). Percent identity with other species by BLAST analysis: Human (100%).
Immunogen Type
Synthetic peptide
Immunogen
PILRB antibody was raised against synthetic peptide C-RVTESKGHSESWH from an internal region of human PILRB (NP_038468.3; NP_839956.1). Percent identity with other species by BLAST analysis: Human (100%).
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-PILRB antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.)

Immunohistochemistry (IHC) (Anti-PILRB antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.)

Immunohistochemistry (IHC)

(Anti-PILRB antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.)

Immunohistochemistry (IHC) (Anti-PILRB antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.)

Immunohistochemistry (IHC)

(Anti-PILRB antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.)

Immunohistochemistry (IHC) (Anti-PILRB antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29,630 Da
NCBI Official Synonym Full Names
paired immunoglobin-like type 2 receptor beta
NCBI Official Symbol
PILRB
NCBI Official Synonym Symbols
FDFACT1; FDFACT2
NCBI Protein Information
paired immunoglobulin-like type 2 receptor beta
UniProt Protein Name
Paired immunoglobulin-like type 2 receptor beta
UniProt Gene Name
PILRB
UniProt Synonym Gene Names
FDFACT
UniProt Entry Name
PILRB_HUMAN

NCBI Description

The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the activating member of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA), that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. This gene is thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating function. [provided by RefSeq, Jun 2013]

Uniprot Description

PILRB: Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: integral to plasma membrane

Molecular Function: protein binding

Biological Process: transmembrane receptor protein tyrosine kinase activation (dimerization); transmembrane receptor protein tyrosine kinase signaling pathway

Research Articles on PILRB

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Product Notes

The PILRB pilrb (Catalog #AAA247388) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human PILRB reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PILRB can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), ELISA (EIA). ELISA, IHC-P (3 - 6 ug/ml) Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH.. Researchers should empirically determine the suitability of the PILRB pilrb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PILRB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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