Western Blot (WB)
(PIGS Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PIGS antibody detected the PIGS protein (arrow).)
Rabbit anti-Human PIGS Polyclonal Antibody | anti-PIGS antibody
PIGS Antibody (C-term)
Western Blot (WB)
(PIGS Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PIGS antibody detected the PIGS protein (arrow).)
Western Blot (WB)
(PIGS Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PIGS antibody detected the PIGS protein (arrow).)
biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a
glycolipid found on many blood cells and serves to anchor proteins
to the cell surface. This gene encodes an essential component of
the multisubunit enzyme, GPI transamidase. GPI transamidase
mediates GPI anchoring in the endoplasmic reticulum, by catalyzing
the transfer of fully assembled GPI units to proteins. [provided by
RefSeq].
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Hong, Y., et al. Mol. Biol. Cell 14(5):1780-1789(2003)
Ohishi, K., et al. J. Biol. Chem. 278(16):13959-13967(2003)
Vainauskas, S., et al. J. Biol. Chem. 277(34):30535-30542(2002)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq, Jul 2008]
Uniprot Description
PIGS: Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates. Belongs to the PIGS family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: endoplasmic reticulum membrane; membrane; GPI-anchor transamidase complex
Molecular Function: protein binding; GPI-anchor transamidase activity
Biological Process: cellular protein metabolic process; attachment of GPI anchor to protein; C-terminal protein lipidation; post-translational protein modification
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Product Notes
The PIGS pigs (Catalog #AAA9209785) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 527-555. The PIGS Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PIGS can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the PIGS pigs for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIGS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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