Rabbit anti-Rat Phospholipase A2 Polyclonal Antibody | anti-Pla2g2a antibody

Rabbit anti-rat Phospholipase A2, membrane associated polyclonal Antibody, HRP conjugated

Gene Names

Pla2g2a; sPLA2

Reactivity

Rat

Applications

ELISA

Purity

Caprylic Acid Ammonium Sulfate Precipitation Purified

Synonyms

Phospholipase A2; Polyclonal Antibody; Rabbit anti-rat Phospholipase A2; membrane associated polyclonal Antibody; HRP conjugated; GIIC sPLA2; Group IIA phospholipase A2; Phosphatidylcholine 2-acylhydrolase 2A; Pla2g2a; anti-Pla2g2a antibody

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Cat. Num. AAA1488623 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Host

Rabbit

Reactivity

Rat

Clonality

Polyclonal

Isotype

IgG

Purity/Purification

Caprylic Acid Ammonium Sulfate Precipitation Purified

Sequence Length

146

Applicable Applications for anti-Pla2g2a antibody

ELISA (EIA)

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Conjugate

HRP

Immunogen

Recombinant rat Phospholipase A2, membrane associated protein

Preparation and Storage

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Related Product Information for anti-Pla2g2a antibody

Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.

NCBI and Uniprot Product Information

NCBI GI #

291621686

NCBI GeneID

29692

NCBI Accession #

NP_113786.3

NCBI GenBank Nucleotide #

NM_031598.3

UniProt Accession #

P14423

Molecular Weight

16,294 Da

NCBI Official Full Name

phospholipase A2, membrane associated

NCBI Official Synonym Full Names

phospholipase A2 group IIA

NCBI Official Symbol

Pla2g2a

NCBI Official Synonym Symbols

sPLA2

NCBI Protein Information

phospholipase A2, membrane associated

UniProt Protein Name

Phospholipase A2, membrane associated

Protein Family

Phospholipase

UniProt Gene Name

Pla2g2a

UniProt Entry Name

PA2GA_RAT

NCBI Description

hydrolyzes acyl group at the sn-2 position of phospholipids, forming non-esterified fatty acids and lysophospholipids; plays a critical role in inflammation; induces proliferation of smooth muscle cells [RGD, Feb 2006]

Uniprot Description

Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:3356705). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Acts as a ligand for integrins. Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1. Independent of its catalytic activity, activates integrins by binding to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and inducing integrin conformational changes and enhanced ligand binding to site 1. Induces cell proliferation in an integrin-dependent manner ().

Research Articles on Pla2g2a

1. a novel inverse recruitment mechanism in which liganded TRbeta recruits corepressors to inhibit PLA2g2a expression.

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Reactivity: n/a

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Product Notes

The Pla2g2a pla2g2a (Catalog #AAA1488623) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-rat Phospholipase A2, membrane associated polyclonal Antibody, HRP conjugated reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Phospholipase A2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the Pla2g2a pla2g2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Phospholipase A2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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