Western Blot (WB)
(WB Suggested Anti-PDP2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate)
Rabbit PDP2 Polyclonal Antibody | anti-PDP2 antibody
PDP2 antibody - middle region
Western Blot (WB)
(WB Suggested Anti-PDP2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate)
Western Blot (WB)
(WB Suggested Anti-PDP2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate)
Target Description: PDP2 catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
NCBI and Uniprot Product Information
NCBI Description
This gene is a mitochondrial protein that functions as a phosphatase and is involved in the enzymatic resetting of the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2016]
Uniprot Description
PDP2: a protein phosphoserine phosphatase associated with the mitochondrial matrix that activates phosphorylated pyruvate dehydrogenase complex by dephosphorylation. The PDPs play crucial roles in switching metabolic flux from glycolysis towards oxidative phosphorylation. Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex . PDP2 consists of only a catalytic subunit. Belongs to the PP2C family.
Protein type: Protein phosphatase, Ser/Thr (non-receptor); Mitochondrial; EC 3.1.3.43
Chromosomal Location of Human Ortholog: 16q22.1
Cellular Component: mitochondrial matrix
Molecular Function: [pyruvate dehydrogenase (lipoamide)] phosphatase activity; magnesium-dependent protein serine/threonine phosphatase activity; metal ion binding
Biological Process: cellular metabolic process; protein amino acid dephosphorylation; pyruvate metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate
Research Articles on PDP2
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Product Notes
The PDP2 pdp2 (Catalog #AAA3213370) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDP2 antibody - middle region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's PDP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the PDP2 pdp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: LQRSILERGF NTEALNIYQF TPPHYYTPPY LTAEPEVTYH RLRPQDKFLV. It is sometimes possible for the material contained within the vial of "PDP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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