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Immunohistochemistry (IHC) (Immunohistochemistry of PDCL3 in mouse liver tissue with PDCL3 antibody at 5 ug/mL.)

Rabbit PDCL3 Polyclonal Antibody | anti-PDCL3 antibody

Anti-PDCL3 Antibody (C-Terminus) IHC-plus

Gene Names
PDCL3; VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A
Reactivity
Mouse, Rat, Human
Applications
Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
Purity
Immunoaffinity purified
Synonyms
PDCL3; Polyclonal Antibody; Anti-PDCL3 Antibody (C-Terminus) IHC-plus; Rabbit Polyclonal to Human PDCL3; Human PDCL3; HTPHLP; PHLP2A; VIAF1; Viral IAP-associated factor 1; PHLP3; Phosducin-like protein 3; PhPL3; VIAF; IAP-associated factor VIAF1; Phosducin-like 3; VIAF-1; anti-PDCL3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Specificity
PDCL3 antibody is human, mouse and rat reactive. PDCL3 antibody is predicted to not cross-react with other members of the PDCL protein family.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
239
Applicable Applications for anti-PDCL3 antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes
IF (20 ug/ml)
IHC-P (10 ug/ml)
WB (1 - 2 ug/ml)
Immunogen
PDCL3 antibody was raised against pDCL3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human PDCL3.
Immunogen Description
PDCL3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human PDCL3.
Immunogen Type
Synthetic peptide
Antigen Modification
C-Terminus
Target Species
Human
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles

Immunohistochemistry (IHC)

(Immunohistochemistry of PDCL3 in mouse liver tissue with PDCL3 antibody at 5 ug/mL.)

Immunohistochemistry (IHC) (Immunohistochemistry of PDCL3 in mouse liver tissue with PDCL3 antibody at 5 ug/mL.)

Immunohistochemistry (IHC)

(Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC)

(Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunofluorescence (IF)

(Immunofluorescence of PDCL3 in mouse liver tissue with PDCL3 antibody at 20 ug/mL.)

Immunofluorescence (IF) (Immunofluorescence of PDCL3 in mouse liver tissue with PDCL3 antibody at 20 ug/mL.)

Western Blot (WB)

(Western blot analysis of PDCL3 in human brain tissue lysate with PDCL3 antibody at 1 ug/ml.)

Western Blot (WB) (Western blot analysis of PDCL3 in human brain tissue lysate with PDCL3 antibody at 1 ug/ml.)
Related Product Information for anti-PDCL3 antibody
PDCL3 Antibody, HTPHLP Antibody, PHLP2A Antibody, VIAF1 Antibody, Viral IAP-associated factor 1 Antibody, PHLP3 Antibody, Phosducin-like protein 3 Antibody, PhPL3 Antibody, VIAF Antibody, IAP-associated factor VIAF1 Antibody, Phosducin-like 3 Antibody, VIAF-1 Antibody Description: Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,614 Da
NCBI Official Full Name
phosducin-like protein 3
NCBI Official Synonym Full Names
phosducin like 3
NCBI Official Symbol
PDCL3
NCBI Official Synonym Symbols
VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A
NCBI Protein Information
phosducin-like protein 3
UniProt Protein Name
Phosducin-like protein 3
Protein Family
UniProt Gene Name
PDCL3
UniProt Synonym Gene Names
PhLP2A; VIAF1; VIAF-1
UniProt Entry Name
PDCL3_HUMAN

NCBI Description

This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]

Uniprot Description

PDCL3: Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination. Belongs to the phosducin family.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; queuine tRNA-ribosyltransferase activity; vascular endothelial growth factor receptor 2 binding

Biological Process: angiogenesis; apoptosis; positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; protein folding; queuosine biosynthetic process; regulation of peptidyl-tyrosine phosphorylation; viral reproduction

Research Articles on PDCL3

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Product Notes

The PDCL3 pdcl3 (Catalog #AAA249746) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PDCL3 Antibody (C-Terminus) IHC-plus reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's PDCL3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA). IF (20 ug/ml) IHC-P (10 ug/ml) WB (1 - 2 ug/ml). Researchers should empirically determine the suitability of the PDCL3 pdcl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDCL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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