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Western Blot (WB) (GLUD2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GLUD2 antibody detected the GLUD2 protein (arrow).)

Rabbit anti-Human GLUD2 Polyclonal Antibody | anti-GLUD2 antibody

GLUD2 Antibody (N-term)

Gene Names
GLUD2; GDH2; GLUDP1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GLUD2; Polyclonal Antibody; GLUD2 Antibody (N-term); Glutamate dehydrogenase 2; mitochondrial; GDH 2; GLUDP1; anti-GLUD2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This GLUD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human GLUD2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
75-103
Sequence Length
558
Applicable Applications for anti-GLUD2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(GLUD2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GLUD2 antibody detected the GLUD2 protein (arrow).)

Western Blot (WB) (GLUD2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GLUD2 antibody detected the GLUD2 protein (arrow).)
Related Product Information for anti-GLUD2 antibody
The protein encoded by this gene is localized to the
mitochondrion and acts as a homohexamer to recycle glutamate during
neurotransmission. The encoded enzyme catalyzes the reversible
oxidative deamination of glutamate to alpha-ketoglutarate. This
gene is intronless.
Product Categories/Family for anti-GLUD2 antibody
References
Spanaki, C., et al. J. Biol. Chem. 285(22):16748-16756(2010)
Plaitakis, A., et al. Eur. J. Hum. Genet. 18(3):336-341(2010)
Zaganas, I., et al. Neurochem. Int. 55 (1-3), 52-63 (2009) :
Mastorodemos, V., et al. Biochem. Cell Biol. 87(3):505-516(2009)
Kanavouras, K., et al. J. Neurochem. 109 SUPPL 1, 167-173 (2009) :

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
61434
NCBI Official Full Name
glutamate dehydrogenase 2, mitochondrial
NCBI Official Synonym Full Names
glutamate dehydrogenase 2
NCBI Official Symbol
GLUD2
NCBI Official Synonym Symbols
GDH2; GLUDP1
NCBI Protein Information
glutamate dehydrogenase 2, mitochondrial
UniProt Protein Name
Glutamate dehydrogenase 2, mitochondrial
UniProt Gene Name
GLUD2
UniProt Synonym Gene Names
GLUDP1; GDH 2
UniProt Entry Name
DHE4_HUMAN

NCBI Description

The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.[provided by RefSeq, Jan 2010]

Uniprot Description

GLUD2: Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission. Homohexamer. Expressed in retina, testis and, at a lower level, brain. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; Mitochondrial; Other Amino Acids Metabolism - D-Glutamine and D-glutamate; Amino Acid Metabolism - arginine and proline; Oxidoreductase; Energy Metabolism - nitrogen; EC 1.4.1.3

Chromosomal Location of Human Ortholog: Xq24-q25

Cellular Component: mitochondrion; cytoplasm

Molecular Function: glutamate dehydrogenase activity; glutamate dehydrogenase [NAD(P)+] activity; GTP binding; ADP binding

Biological Process: glutamate catabolic process; glutamate metabolic process; glutamate biosynthetic process

Research Articles on GLUD2

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Product Notes

The GLUD2 glud2 (Catalog #AAA9213200) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 75-103. The GLUD2 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GLUD2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the GLUD2 glud2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GLUD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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