Testing Data
Rabbit PBR Polyclonal Antibody | anti-PBR antibody
PBR Antibody
Testing Data
Testing Data
NCBI and Uniprot Product Information
Uniprot Description
TSPO: Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells. Belongs to the TspO/BZRP family. Interacts with BZRAP1. May interact with STAR. Interacts with MOST-1. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; Mitochondrial; Receptor, misc.; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: mitochondrial outer membrane; nuclear membrane; membrane; intracellular membrane-bound organelle; mitochondrion; cytoplasm; integral to membrane
Molecular Function: androgen binding; benzodiazepine receptor activity
Biological Process: positive regulation of apoptosis; negative regulation of nitric oxide biosynthetic process; chloride transport; regulation of steroid biosynthetic process; negative regulation of tumor necrosis factor production; glial cell migration; signal transduction; lipid transport; synaptic transmission; behavioral response to pain; positive regulation of mitochondrial depolarization; transport; ion transport; positive regulation of calcium ion transport; steroid biosynthetic process
Research Articles on PBR
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Product Notes
The PBR tspo (Catalog #AAA840156) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PBR Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PBR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blot analysis (0.5-4 ug/ml) and Immunohistochemistry (2.5 ug/ml). However, the optimal conditions should be determined individually. Researchers should empirically determine the suitability of the PBR tspo for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PBR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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