Western Blot (WB)
(Western blot analysis of Jurkat cell lysates (lane 1), recombinant TSPO (lane 2) and rat kidney tissue lysate (lane 3) probed with Rabbit anti TSPO antibody)
Rabbit anti-Mouse TSPO Polyclonal Antibody | anti-TSPO antibody
RABBIT ANTI TSPO
WB: 0.5 - 4.0 ug/ml
Western Blotting: Rabbit anti TSPO antibody recognizes a band of approximately 50 kDa (corresponding to the TSPO-VDAC complex) in Jurkat cell lysates and rat kidney tissue lysates
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Shelf Life: 12 months from date of despatch
Western Blot (WB)
(Western blot analysis of Jurkat cell lysates (lane 1), recombinant TSPO (lane 2) and rat kidney tissue lysate (lane 3) probed with Rabbit anti TSPO antibody)
Western Blot (WB)
(Western blot analysis of Jurkat cell lysates (lane 1), recombinant TSPO (lane 2) and rat kidney tissue lysate (lane 3) probed with Rabbit anti TSPO antibody)
NCBI and Uniprot Product Information
Uniprot Description
TSPO: Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells. Belongs to the TspO/BZRP family. Interacts with BZRAP1. May interact with STAR. Interacts with MOST-1. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Receptor, misc.; Apoptosis; Mitochondrial; Membrane protein, integral
Cellular Component: cytoplasm; integral to membrane; intracellular membrane-bound organelle; membrane; mitochondrial outer membrane; mitochondrion; nuclear membrane
Molecular Function: androgen binding; benzodiazepine receptor activity
Biological Process: behavioral response to pain; chloride transport; glial cell migration; ion transport; lipid transport; negative regulation of nitric oxide biosynthetic process; negative regulation of protein ubiquitination; negative regulation of tumor necrosis factor production; positive regulation of apoptosis; positive regulation of calcium ion transport; positive regulation of mitochondrial depolarization; regulation of steroid biosynthetic process; steroid biosynthetic process; synaptic transmission; transport
Research Articles on TSPO
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Product Notes
The TSPO tspo (Catalog #AAA224857) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI TSPO reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TSPO can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 2.5 ug/ml WB: 0.5 - 4.0 ug/ml Western Blotting: Rabbit anti TSPO antibody recognizes a band of approximately 50 kDa (corresponding to the TSPO-VDAC complex) in Jurkat cell lysates and rat kidney tissue lysates Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls. Researchers should empirically determine the suitability of the TSPO tspo for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSPO, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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