Immunohistochemistry (IHC)
(IHC staining of cerebellar Purkinje cell layer in P15 rat brain (50um section) using antibody MBS612710. Source: http://stke.sciencemag.org/cgi/data/sigtrans;1/41/ra8/DC1/1)
Guinea pig anti-Human, Rat P2X2 Receptor Polyclonal Antibody | anti-P2RX2 antibody
P2X2 Receptor
Serum
Serum
Dilution: Western Blot: 1:500
Immunohistochemistry: 1:500
Immunocytochemistry: 1:500
Immunohistochemistry (IHC)
(IHC staining of cerebellar Purkinje cell layer in P15 rat brain (50um section) using antibody MBS612710. Source: http://stke.sciencemag.org/cgi/data/sigtrans;1/41/ra8/DC1/1)
Immunohistochemistry (IHC)
(IHC staining of cerebellar Purkinje cell layer in P15 rat brain (50um section) using antibody MBS612710. Source: http://stke.sciencemag.org/cgi/data/sigtrans;1/41/ra8/DC1/1)
Immunohistochemistry (IHC)
(IHC staining of rat brainsterm using MBS612710.)
Immunohistochemistry (IHC)
(IHC staining of rat brainsterm using MBS612710.)
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013]
Uniprot Description
P2X2: Binding of this ligand-gated ion channel to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Belongs to the P2X receptor family. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, ligand-gated; Channel, cation
Chromosomal Location of Human Ortholog: 12q24.33
Cellular Component: presynaptic membrane; cell surface; cell soma; integral to plasma membrane; apical plasma membrane; postsynaptic density; dendritic spine; terminal button; integral to nuclear inner membrane; receptor complex
Molecular Function: identical protein binding; zinc ion binding; mercury ion binding; drug binding; ligand-gated ion channel activity; cadmium ion binding; purinergic nucleotide receptor activity; nickel ion binding; phosphoinositide binding; copper ion binding; cobalt ion binding; ATP binding; ATP-gated cation channel activity
Biological Process: urinary bladder smooth muscle contraction; peristalsis; sensory perception of taste; protein heterooligomerization; generation of action potential; skeletal muscle fiber development; positive regulation of calcium-mediated signaling; detection of hypoxic conditions in blood by carotid body chemoreceptors; response to carbohydrate stimulus; response to ATP; behavioral response to pain; sensory perception of sound; response to hypoxia; neuromuscular synaptic transmission; neuromuscular junction development; protein homooligomerization
Disease: Deafness, Autosomal Dominant 41
Research Articles on P2RX2
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Product Notes
The P2RX2 p2rx2 (Catalog #AAA612710) is an Antibody produced from Guinea pig and is intended for research purposes only. The product is available for immediate purchase. The P2X2 Receptor reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's P2X2 Receptor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC). Suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry. Dilution: Western Blot: 1:500 Immunohistochemistry: 1:500 Immunocytochemistry: 1:500. Researchers should empirically determine the suitability of the P2RX2 p2rx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "P2X2 Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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