Western Blot (WB)
(OXTR Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the OXTR antibody detected the OXTR protein (arrow).)
Rabbit anti-Human, mouse OXTR Polyclonal Antibody | anti-OXTR antibody
OXTR Antibody (N-term)
Western Blot (WB)
(OXTR Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the OXTR antibody detected the OXTR protein (arrow).)
Western Blot (WB)
(OXTR Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the OXTR antibody detected the OXTR protein (arrow).)
coupled receptor family and acts as a receptor for oxytocin. Its
activity is mediated by G proteins which activate a
phosphatidylinositol-calcium second messenger system. The
oxytocin-oxytocin receptor system plays an important role in the
uterus during parturition.
Kim, H.S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15717-15721(2010)
Thompson, R.J., et al. Psychoneuroendocrinology (2010) In press :
Tost, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(31):13936-13941(2010)
Amrani, Y., et al. Respir. Res. 11, 104 (2010) :
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]
Uniprot Description
OXTR: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1
Chromosomal Location of Human Ortholog: 3p25
Cellular Component: microvillus; cell-cell adherens junction; integral to plasma membrane; apical plasma membrane; plasma membrane
Molecular Function: oxytocin receptor activity; peptide hormone binding; peptide binding; vasopressin receptor activity
Biological Process: lactation; response to peptide hormone stimulus; response to anoxia; heart development; female pregnancy; positive regulation of synaptic transmission, glutamatergic; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; muscle contraction; response to drug; maternal behavior; eating behavior; response to amphetamine; positive regulation of synaptic transmission, GABAergic; social behavior; response to cocaine; sleep; memory; cellular response to hormone stimulus; G-protein coupled receptor protein signaling pathway; positive regulation of synaptogenesis; telencephalon development; suckling behavior; gut development; regulation of systemic arterial blood pressure by vasopressin; response to cytokine stimulus; maternal process involved in parturition; positive regulation of vasoconstriction; sperm ejaculation; response to progesterone stimulus; positive regulation of blood pressure
Research Articles on OXTR
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Product Notes
The OXTR oxtr (Catalog #AAA9212306) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 8-36. The OXTR Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's OXTR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the OXTR oxtr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OXTR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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