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Rabbit anti-Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody | anti-OSGIN1 antibody

Biotin-Linked Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1)

Gene Names
OSGIN1; BDGI; OKL38
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Synonyms
Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1); Polyclonal Antibody; Biotin-Linked Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1); BDGI; OKL38; Bone Marrow Stromal Cell-Derived Growth Inhibitor; Pregnancy Induced Growth Inhibitor; Ovary; kidney and liver protein 38; anti-OSGIN1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Concentration
500ug/ml (varies by lot)
Sequence Length
477
Applicable Applications for anti-OSGIN1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Conjugation
Biotin
Cross Reactivity
Human
Immunogen
OSGIN1 (Gly25~Val281)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
– Da
NCBI Official Full Name
oxidative stress-induced growth inhibitor 1
NCBI Official Synonym Full Names
oxidative stress induced growth inhibitor 1
NCBI Official Symbol
OSGIN1
NCBI Official Synonym Symbols
BDGI; OKL38
NCBI Protein Information
oxidative stress-induced growth inhibitor 1
UniProt Protein Name
Oxidative stress-induced growth inhibitor 1
UniProt Gene Name
OSGIN1
UniProt Synonym Gene Names
OKL38; huOKL38

NCBI Description

This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product. [provided by RefSeq, Aug 2011]

Uniprot Description

OSGIN1: Regulates the differentiation and proliferation of normal cells through the regulation of cell death. Belongs to the OKL38 family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 16q23.3

Molecular Function: growth factor activity; oxidoreductase activity; protein binding

Biological Process: cell differentiation; multicellular organism development; negative regulation of cell growth; positive regulation of apoptosis

Research Articles on OSGIN1

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Product Notes

The OSGIN1 osgin1 (Catalog #AAA2096121) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Biotin-Linked Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the OSGIN1 osgin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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